Hypothalamus-Pituitary Flashcards
Pituitary gland is known as the
master gland
anterior lobe grows
upward from roof of the mouth
anatomical structures of the anterior lobe include (3 things)
pars distills, pars tubercles, intermedia
histology of the anterior lobe include 35% acidophils which are (what two things?)
lactotrophs - prolactin
somatotrophs - growth hormone
anatomical structures of the posterior lobe
pars nervosa
infundibular stalk
median eminence
blood supply for the anterior lobe comes from the
long portal vessels from medial eminence
posterior lobe grows
downward from they hypothalamus
TRH comes from the
paraventricular nucleus
GnRH comes from the
arcuate nucleus
GIH comes from the
anterior hypothalamus
PIH comes from the
arcuate nucleus
CRH comes from the
paraventricular nucleus
GFH comes from the
arcuate nucleus
ADH functions
works on kidneys to make aquaporins so water is filtered
alos vasoconstriction
oxytocin function
contracts myoepithelial cells of mammary gland
contracts myometrium of uterus
chemistry of ADH and oxytocin - they are both
nonapeptides (9aa)
ADH and oxytocin are synthesized as
prohormoens
ADH is regulated by what 2 things?
plasma volume and sodium
decreased plasma volume does what to ADH?
increases ADH
increased plasma sodium does what to ADH?
increased ADH
increased angiotensin II = what to ADH?
increased ADH
ADH is inhibited by what hormone?
atrial nature tic hormone
does morphine increase or decrease ADH?
increase
does alcohol increase or decrease ADH?
decrease
you don’t maintain your water so you pee
action of ADH
increases vascular contraction and increases blood pressure
promotes water reabsorption in renal tubules
what increases oxytocin secretion?
suckling
intercoarse
estrogens
what increases ADH secretion?
receptor singles through phosphatidylinostiol pathway
