Growth Hormone Flashcards

1
Q

source of growth hormone is the

A

pituitary gland

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2
Q

what specific cells produce growth hormone?

A

somatotrophs

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3
Q

chemistry of growth hormone

A

it’s a long peptide

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4
Q

regulation of growth hormone starts where?

A

the hypothalamus

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5
Q

what two hormones in the hypothalamus are involved with growth hormone regulation?

A

GRH and GIH

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6
Q

GRH does what to growth hormone secretion?

A

increases it

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7
Q

GIH does what to growth hormone secretion?

A

decreases it

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8
Q

growth hormone stimulates what hormone in the liver?

A

IGF1

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9
Q

what does IGF1 stimulate?

A

bone growth

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10
Q

where is growth hormone stored?

A

in granules

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11
Q

what stimuli increase growth hormone secretion?

A

stress/exercise
low plasma or glucose or FFA
SWS
after each meal

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12
Q

the action of growth hormone is anabolic so it…..

A

makes proteins

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13
Q

since growth hormone makes proteins what does it do to amino acids?

A

lowers amino acids in the plasma

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14
Q

what does growth hormone to do glucose and FFA levels?

A

elevates

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15
Q

pathology of growth hormone - dwarfism

A

GH deficiency and receptor deficiency

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16
Q

pathology of growth hormone - giatism

A

GH excess in children

endochondral growth

17
Q

pathology of growth hormone - acromegaly

A

GH excess in adults

intramembranous growth