Growth Hormone Flashcards
source of growth hormone is the
pituitary gland
what specific cells produce growth hormone?
somatotrophs
chemistry of growth hormone
it’s a long peptide
regulation of growth hormone starts where?
the hypothalamus
what two hormones in the hypothalamus are involved with growth hormone regulation?
GRH and GIH
GRH does what to growth hormone secretion?
increases it
GIH does what to growth hormone secretion?
decreases it
growth hormone stimulates what hormone in the liver?
IGF1
what does IGF1 stimulate?
bone growth
where is growth hormone stored?
in granules
what stimuli increase growth hormone secretion?
stress/exercise
low plasma or glucose or FFA
SWS
after each meal
the action of growth hormone is anabolic so it…..
makes proteins
since growth hormone makes proteins what does it do to amino acids?
lowers amino acids in the plasma
what does growth hormone to do glucose and FFA levels?
elevates
pathology of growth hormone - dwarfism
GH deficiency and receptor deficiency