hypohidrosis and anhidrosis

Question 1

What are 5 general pathologies that cause hypohidrosis/anhidrosis?

Answer 1

1. central/neuropathic disorders (spinal cord injuries)
2. medications (anticholinergics)
3. congenital alterations of sweat glands (ectodermal dysplasias)
4. acquired destruction/atrophy of sweat glands (burns, scleroderma, morphea, GVHD)
5. sweat gland obstruction (miliaria, ichthyoses, psoriasis, eczematous dermatoses)

Question 2

Management of hypohidrosis:

Answer 2

• discontinue any offending meds if present
• avoid hyperpyrexia and maintain a cool environment
• gentle exfoliation if obstructed sweat glands