Hidradenitis suppurativa

Question 1

What is the believed pathogenesis of HS?

Answer 1

1. follicular occlusion
2. Immune dysregulation

Question 2

What are the associations with HS?

Answer 2

• smoking
• obesity
• metabolic syndrome
• depression

Question 3

Clinical presentation of HS:

Answer 3

• begin as recurrent tedner/painful inflammatory nodules and sterile abscesses
• Later develop sinus tracts (superficial sinus tracts present as double-ended comedones)
  *

Question 4

Histopath of HS:

Answer 4

suppurative folliculitis with abscess formation, follicular plugging, granulation tissue, and inflammation that can involve aprocrine glands, late stages can have fibrosis