Hypo & Hyperpigmentation Flashcards
1
Q
what is vitiligo
A
chronic depigmentation disorder due to T-cell response to melanocytes.
2
Q
s/s of vitiligo
A
symmetrical well demarcated macules of complete pigment loss
3
Q
what is post-inflammatory hypopigmentation
A
may occur following eczema or psoriasis
4
Q
what is albinism
A
reduced/absent pigment synthesis in skin, hair and eyes.
5
Q
what are freckles?
A
clumpy distribution of melanocytes
6
Q
gene mutation responsible for freckles
A
1 copy of MC1R
7
Q
actinic lentigines are…?
A
age spots related to long term UV exposure
8
Q
s/s of actinic lentigines?
A
persistant (don’t fade in winter) pigmented macules similar to freckles found on sun exposed sites
