Hypertensive Heart Disease & Cor Pulmonale Flashcards

1
Q

if the radius of a blood vessle decreases, what happens to the resistance and blood flow

A
  • poiseuille’s law
  • resistance to blood flow increases
  • blood flow decreases
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2
Q
  • how can we preserve blood flow is the radius decreases?

- what does this mean for the heart?

A
  • increase change in pressure

- it has to work harder

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3
Q

when you increase the radius of vasculature, what happens to afterload

A

decrease

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4
Q

double product

A
  • amount of O2 used by the heart

- DP = HR x SBP

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5
Q

normal BP

A

less than 120 and less than 80

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6
Q

elevated BP

A

120-129 and less than 80

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7
Q

high blood pressure, HTN stage 1

A

130-139 or 80-89

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8
Q

high blood pressure, hypertension stage 2

A

140 or higher or 90 or higher

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9
Q

hypertensive crisis

A

higher than 180 and/or higher than 120

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10
Q

why do people stop taking their anti-hypertensive medication

A
  • unpleasant side effects
  • interference with sexual function
  • cost
  • taking anti-hypertensives does not change the way a pt feels so why take them
  • increased age
  • gender: women
  • african american
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11
Q

what is the relationship between BP and risk of CVD event

A
  • positive, continuous, consistent, independent of other risk factors
  • higher chance of having a MI, HF, PVD, carotid atherosclerosis, stroke, left ventricular hypertrophy and kidney disease
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12
Q

what does controlling systolic HTN help do

A
  • reduce total mortality, cardiovascular mortality, stroke, HF events
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13
Q

essential or primary HTN

A
  • no known cause
  • increases with age
  • reduced vascular compliance
  • progressive
  • 90% of all cases
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14
Q

secondary HTN

A
  • caused by conditions that affect your kidneys, arteries, heart or endocrine system
  • 10% of all HTN cases
  • treatment focuses on management of the underlying cause
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15
Q

how does uncontrolled HTN and kidney disease relate

A
  • cause arteries around the nephron of the kidney to narrow, weaken and harden
  • unable to deliver blood to kidney tissue
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16
Q

what happens to the filtration at the level of the nephron when you have HTN

A

reduced, GFR also declines

17
Q

since you have decreased filtration, how do the kidneys respond?

A
  • the kidneys perceive this as a reason to increase water and sodium reabsorption leading in increased blood pressure (hypervolemia & hypernatremia)
18
Q

what is the net effect of HTN & kidney disease

A
  • increase preload
  • increase total peripheral resistance
  • decrease ability to appropriately control whole body BP
  • downward spiral of kidney fxn
19
Q

diabetes, kidney disease, HTN; how are they related?

A
  • elevated glucose levels damage glomerular filtration and reduce GFR
  • kidneys respond by reabsorbing more water and sodium, increasing fluid volume and blood pressure
20
Q

how does HTN result in a pathologic heart?

A
  • increased afterload –> thickening of the heart muscle (compensated)
  • as it continues, cellular, subcellular and vascular changes occur in the heart rendering it less effective (decompensated)
  • lumen of the left ventricle progressively dilates and its walls thin
  • LV EF declines
21
Q

malignant HTN signs and symptoms

A
  • > 180/120
  • changes in vision
  • cough
  • nausea or vomitting
  • numbness, weakness in arms, legs, face
  • chest pain
  • anxiety
  • SOB
  • headaches
22
Q

cor pulmonale

A
  • pulmonary heart disease
  • enlargement of the right ventricle caused by a primary pulmonary disorder
  • identifies the pathologic effects of pulmonary dysfunction on the right side of the heart
23
Q

pulmonary HTN

A

MAP > 25mmHg or systolic pressure > 35mmHg

24
Q

how can the right side of the heart move the same volume of blood at a much lower pressure?

A
  • RV has the same stroke volume as LV
  • shorter length of tubing
  • more compliant vessels means less resistance to flow
  • much lower impact of gravity on blood flow
24
Q

cor pulmonae symptoms

A
  • chest pain
  • fatigue
  • bilateral LE edema
  • syncope/passing out
25
Q

diseases associated with cor pulmonale

A
  • COPD
  • diffuse pulmonary interstitial fibrosis
  • extensive, persistent atelectasis
  • cystic fibrosis
  • pulmonary embolism
26
Q

diseases of pulmonary vessels associated with cor pulmonale

A

pulmonary vascular sclerosis

drug, toxin, XTR induced vascular sclerosis

27
Q

diseases affecting chest wall movement

A

kyphoscolosis
marker obesity
neuromuscular disease

28
Q

diseases inducing pulmonary arteriolar constriction

A

hypoxemia - airway obstruction, hypoventilation, chronic altitude sickness

29
Q

what is exercise prescription for people with pulmonary artery HTN

A
  • exercise can be good
  • light resistance of small muscle groups and light to moderate aerobic activity is acceptable
  • outdoor activity should be avoided during hot, humid or very cold weather