Cardiomyopathies Flashcards
dyspnea
shortness of breath
tachypnea
increased respiratory rate
syncope
fainting
tachycardia
increased heart rate
cardiomyopathy
- disorder within the cardiac myocytes themselves which results in abnormal cellular and cardiac performance
what happens to EF when you have cardiomyopathy
reduces - predicts mortality and morbidity
dilated cardiomyopathy
- chamber dilation and contractile impairment resulting in decreased EF & SV
- ballooning of the LV
- leads to heart failure
what does cardiac remodeling lead to in dilated cardiomyopathy
- heavier than normal heart
- hypertrophied cardiac myocytes
- loss of myofibrils, reduced mitochondrial function
- fibrosis occurs
- chamber walls thin
causes of dilated cardiomyopathy
- genetic mutations
- viral infections like HIV
- various toxins
- metabolic disorders
- myocarditis
symptoms of dilated cardiomyopathy
- fatigue
- dyspnea on exertion
- SOB
- cough
- orthopnea
- paroxysmal nocturnal dyspnea
- edema
- weight gain
- abdominal girth
signs of dilated cardiomyopathy
- tachypnea
- tachycardia
- HTN or hypotension
what happens to LV EDV in dilated cardiomyopathy
- the overstretching increases it, leads to failure of the myocardial contractile unit
- frank starling compromised
hypertrophic cardiomyopathy
- common cause of death in healthy young people
- thicken LV wall with a non-dilated LV chamber –> EDV limited
- dont have HTN but have chronic afterload on the heart
gene defects of hypertrophic cardiomyopathy
heart lays down more sarcomeres than needs = compromises movement of sarcomeres
obstructive HCM
septal wall thickens and the LV free wall of the ventricles stiffen
obstructing blood flow into the aorta