Hypersensitivity Flashcards
1
Q
What is primary immunodeficiency?
A
Immunodeficiency that is not caused by an agent and is usually genetic
B cell deficiency or IgA most common
2
Q
What is secondary immunodeficiency?
A
When an individual is immunocompromised due to infection, drugs, chronic disease
3
Q
What is type 1 hypersensitivity?
A
IgE mediated
Innocuous antigen e.g. pollen
Example: allergy
4
Q
What is type 2 hypersensitivity?
A
IgG or IgM mediated
Cellular antigen
Example: rhesus baby
5
Q
What is type 3 hypersensitivity?
A
IgG mediated
Soluble antigen
Example: rheumatoid arthritis
6
Q
What is type 4 hypersensitivity?
A
T-cell mediated
Cellular antigen
Example: diabetes mellitus
7
Q
Which types of hypersensitivity are associated with autoimmunity?
A
Type 2,3,4
