Hypersensitivity

Question 1

___________________

Allergies

Answer 1

Type I Hypersensitivity

Allergies

Question 2

________________

Exaggerated Th2 response

Answer 2

Type I hypersensitivity

Exaggerated Th2 response

Question 3

_________________

Excessive amounts of IgE

Answer 3

**Type I hypersensitivity **

Excessive amounts of IgE

Question 4

Atopy

Answer 4

Predisposition towards developing certain allergic hypersensitivity reactions

Question 5

________ and ___________ contribute to allergies.

Answer 5

**Genes **and environmental factors contribute to allergies.

Question 6

______________ play an important role in hypersensitivity

Answer 6

Intestinal microflora play an important role in hypersensitivity

Question 7

_____________ can cause hypersensitivity

Answer 7

Parasitic worms can cause hypersensitivity

Question 8

Hypersensitivity

Answer 8

Body’s reaction towards an antigen is blown out of proportion and causes severe reactions

Question 9

Hypersensitivity requires __________ state of the host

Answer 9

Hypersensitivity requires pre-sensitized state of the host

Question 10

Type I hypersensitivity = _____________ hypersensitivity

Answer 10

Type I hypersensitivity =** immediate** hypersensitivity

Question 11

_____________

FcER has high affinity and irreversible binding

Answer 11

Type I Hypersensitivity

FcER has high affinity and irreversible binding

Question 12

FcER1 is present on _______, ________, _________, _________, ___________ and __________.

Answer 12

FcER1 is present on mast cells, basophils, neutrophils, eosinophils, dendritic cells and platelets.

Question 13

FcERII is present on ______, __________, _________, ________, __________, and ___________.

Answer 13

FcERII is present on B cells, NK cells, macrophages, dendritic cells, eosinophils, and platelets.

Question 14

FcER

Answer 14

Receptor that contributes to the immune system by allowing the specific cells it is found on to bind to antibodies that are attached to infected cells

Question 15

Diagnosis of type I hypersensitivity by:

Answer 15

Intradermal skin testing

Passive cutaenous anaphylaxis

Measuring IgE concentration

Question 16

Treatment of type I hypersensitivity

Answer 16

Avoid exposure

Corticosteroids

Antihistamines

B stimulants or alpha antagonists

Question 17

Type II hypersensitivity = __________

Answer 17

Type II hypersensitivity = Antibody mediated cytotoxicity

Question 18

Type II hypersensitivity involves ________ working as antigens

Answer 18

Type II hypersensitivity involves RBC working as antigens

Question 19

Type III hypersensitivity = _____________

Answer 19

Type III hypersensitivity = Immune complex hypersensitivity

Question 20

Local type of type III hypsersensitivity

Answer 20

immune complexes are formed within the tissue

Question 21

Generalized type of type III hypersensitivity

Answer 21

immune complexes are formed with the blood stream and deposited in glomeruli in the kidney

Question 22

Type IV hypersensitivity = _____________

Answer 22

Type IV hypersensitivity = Delayed type hypersensitivity (DTH)

Question 23

Type IV hypersensitivity involves _____________.

Answer 23

Type IV hypersensitivity involves injected antigens (vaccines).

Question 24

Measurement of __________ using hypersensitivity, one can separate non-dividing cells from dividing cells and be able to count the number of proliferating cells.

Answer 24

Measurement of proliferation using hypersensitivity, one can separate non-dividing cells from dividing cells and be able to count the number of proliferating cells.

Question 25

Measurement of __________ using hypersensitivity one can measure the cells that are killed and not killed during a reaction.

Answer 25

Measurement of cell death using hypersensitivity one can measure the cells that are killed and not killed during a reaction.