Hypersensitivity Flashcards

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1
Q

What are the Gell-Coombs classification of hypersensitivity reactions ?

A
  1. Anaphylactic/Atopic
  2. Antibody-dependent cytotoxic
  3. immune complex-mediated
  4. T-cell mediated/Delayed
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2
Q

Describe Allergy - Type 1 hypersensitivity

A
  • immune mediated response to usually innocuous environmental antigens
  • involves prior exposure to antigen resulting in sensitisation of individuals
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3
Q

Describe Atopy - type 1 hypersensitivity

A
  • susceptible to immediate HS mediated by IgE
  • affects parts of the body not In direct contact with allergen
  • used to describe allergic rhinitis, asthma & eczema
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4
Q

Describe Type 1 - IgE mediated hypersensitivity

A
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