Hypersensitivity Flashcards
1
Q
Type 1 Hypersensitivity occurs after ____, when immune system develops ____. Ag-specific ___ bound to ____ on ____. Receptor __ releases __.
A
Initial exposure, IgE, FceRI, mast/baso/eos
Crosslinking, Histamine and TNF-alpha
2
Q
Type 4 Hypersensitivity
A
T-cell based
Delayed Type (TB)
Contact (haptens, metal ions)
Gluten-sensitive enteropathy (gliadin)
3
Q
IgE-mediated allergy
A
Systemic anaphylaxis Wheal and flare (local) Allergic rhinitis (hay fever) Bronchial asthma Food allergy
4
Q
Two types of mast cells
A
Connective tissue
Skin (mostly IgE)
