Hypersensitivities Flashcards
1
Q
what are the names of all 4 of the types of hypersensitivities
A
type I - immediate
type II - antibody-mediated
type III - immune complex-mediated
type IV - cell mediated
2
Q
allergies are mostly which type
A
type I (some type IV)
3
Q
in general describe type I
A
crosslinking of IgE antibodies bound to mast cells by antigen (allergen)
4
Q
in general describe type II
A
binding of IgG or IgM antibodies to antigens present on cells or basement membranes
5
Q
in general describe type III
A
deposition of immune complexes (Ag/Ab) in tissues
6
Q
in general describe type IV
A
T cell-directed mechanisms of tissue injury
