Hyperparathyroidism Flashcards
1
Q
Hyperparathyroidism Pathology
A
Hypersecretion of PTH
2
Q
Primary Hyperparathyroidism
A
Due to parathyroid pathology (adenoma, hyperplasia, carcinoma)
- Sporadic
- Familial (MEN-1)
3
Q
Secondary Hyperparathyroidism
A
Physiological response to other disease: chronic renal failure, decreased calcium/vitamin D
4
Q
Hyperparathyroidism Symptoms
A
- Depression
- Cognitive change
- Change in sleeping pattern
- Myalgias
- Fatigue
- Polyuria, polydipsia
- Nausea, loss of appetite
- Constipation
- Abdominal pain
- Bone and joint pain
5
Q
Hyperparathyroidism Complications
A
- Osteoporosis
- Kidney stones
- Cardiovascular disease
6
Q
Hyperparathyroidism Investigations
A
- Palpable neck mass
- Blood test: PTH, calcium
- Urine test: 24-hour calcium
- Imaging: DEXA, US, CT kidney
7
Q
Hyperparathyroidism Management
A
- Surgical resection
- Monitoring
- Biphosphonates