Acromegaly Flashcards
1
Q
Acromegaly Pathology
A
Hypersecretion of GH
2
Q
Acromegaly Aetiology
A
Anterior pituitary somatotroph adenoma
3
Q
Acromegaly Symptoms
A
- Facies: course features
- Soft tissue overgrowth: hands, feet, carpal tunnel syndrome
- Sweating
- Fatigue
- Snoring
- Joint pain
- Sexual dysfunction
- Headaches
- Increased appetite/polyuria
- Visual field defects
4
Q
Acromegaly Complications
A
- Osteoporosis
- Hypertension
- Sleep apnoea
- Diabetes
5
Q
Acromegaly Investigations
A
- serum IGF-1
- OGTT
- serum GH
- imaging
- ophthalmology review
6
Q
Acromegaly Management
A
- Transphenoidal surgery
- Somatostatins
- Dopamine agonist
- GH receptor antagonist
- Radiotherapy
- Testosterone