Hyperlipidemia

Question 1

What are the 4 groups of people who should be on statins

Answer 1

1. Anyone with ASCVD
2. Adults with LDL > 190mg
3. 40-75 y/o with DM and an LDL with 70-189 mg/dL
4. 40-75 y/o with 10 year risk greater or equal to 7.5%

Question 2

What are the treatment recommendations and for anyone with ASCVD and adults with an LDL > 190 mg/dL

Answer 2

High intensity statin- 50% reduction in LDL

1. Atorvastatin 40-80mg
2. Rosuvastatin 20-40mg

Question 3

What are the treatment recommendations for patients with DM and LDL of 70-189 mg/dL

Answer 3

Moderate intensity statin=30-50% reduction of LDL

1. Atorvastatin 10-20mg
2. Simvastatin 20-40mg
3. Pravastatin 40mg

Question 4

What are the treatment recommendations for 4-75 y/o with a 10 year risk factor of 7.5% or more

Answer 4

Moderate to High intensity statin

Question 5

What are criteria for Therapeutic Lifestyle Changes?

Answer 5

1. Approach - start small and encourage pt to make a goal
2. Start a conversation and follow up
3. Encourage change for health, lipids, BP,
4. Diets and visual handouts

Question 6

What is Familial Hypercholesterolemia?

Answer 6

LDL receptors are absent or dysfunctional

• Homozygotes = LDL 8x normal
• Heterozygotes = LDL 2x normal

Question 7

What is Familial Hyperchylomicronemia

Answer 7

Lipoprotein lipase abnormality-the enzyme that helps peripheral tissue to take up TG from chymomicros and VLDL is disrupted