Hunger and the Chemical Senses Flashcards
Glucose
primary fuel for the brain
Glycogen
Stored form of glucose
Insulin
Stimulates glucose metabolism and glycogen synthesis
CCK
Responsible for short term satiation and terminating meals
NPY
Stimulates appetite and food consumption
Leptin
- High levels inhibit NPY, lower appetite
Low levels promote feeding, energy conservation
Fat (Adipose Tissue)
- Has more than 2x the energy that carbs have
Found virtually in all parts of the body
Leptin Resistant
at a certain point, leptins ability to inhibit appetite is reduced
Endogenous Opioids
- Naturally occurring chemical substances that have morphine like analgesic actions in the body
- Contributes to palatability and reward-driven feeding
Overeating could be reflective of a maladaptive opioid-mediated reward-driven feeding mechanism
- Contributes to palatability and reward-driven feeding
Tastes we can Detect
- Sweet: energy rich foods
- Salty: identify and ingest essential electrolytes
- Bitter: warn you of harmful, spoiled, or poisonous foods
- Sour: harmful, spoiled or poisonous foods
Umami (Savoury): detects amino acids glutamate and aspartate
Nasal Pharynx
more sophisticated ability to sense flavour
Smell
has a direct link to the cortex without going through the thalamus
Olfactory Receptors
respond to a range of stimuli
Glomeruli
each receive input from thousands of olfactory receptors
Output from glomeruli goes to higher order brain areas