Human Phys 7.2

Question 1

Where do RBC stay within?

Answer 1

Vascular system

Question 2

What do RBC lack?

Answer 2

Nucleus

ER

Mitochondria

Ribosomes

Question 3

What can RBC not do?

Answer 3

Grow or divide

Question 4

What is the lifespan of a RBC?

Answer 4

120 days

Question 5

What happens to worn out RBC?

Answer 5

Phagocytoses and digested by macrophages in the liver and spleen

Question 6

What can happen if hemoglobin is not kept inside the RBC?

Answer 6

Can leak through capillary membranes into interstitial spaces or glomerular filtrate

Question 7

What does the RBC contain large amounts of?

Answer 7

Enzyme carbonic anhydrase

Question 8

What is the quantity of RBC in healthy men?

Answer 8

5.2 million

Question 9

What is the quantity of RBC in healthy women?

Answer 9

4.7 million

Question 10

How much hemoglobin can RBC hold?

Answer 10

Up to 34 grams

Question 11

How much hemoglobin do men hold?

Answer 11

15 gram/deciliter
(Women is 14)

Question 12

How much O2 can 1 gram of hemoglobin hold?

Answer 12

1.34 mL

Question 13

What is the RBC production in different body parts as you get older?

Answer 13

High in vertebrae, sternum, and rib

Low in tibia and femur

Question 14

What makes up a tiny portion of the bone marrow population?

Answer 14

Stem cells (1 in 10000)

Question 15

Colony stimulating factor

Answer 15

Glycoproteins that may circulate in the blood and act as hormones or act directly in the bone marrow as local mediators

Question 16

What is a colony stimulating factor?

Answer 16

Erythropoietin

Question 17

Why does someone become anemic when both kidneys do not work?

Answer 17

Due to loss of EPO production

Question 18

Angiogenesis

Answer 18

Growth of new blood vessels

Question 19

How can low O2 promote angiogenesis?

Answer 19

Low O2 leads to high HIF which leads to VEGF which leads to angiogenesis

Question 20

What is VGEF?

Answer 20

Vascular growth factor