Human Phys 6.3 Flashcards

1
Q

Lung mechanics is the study of what?

A

Mechanical properties of the lung and chest wall, including the diaphragm, abdominal cavity, and abdominal muscles

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2
Q

What is death from lung disease almost always due to?

A

Respiratory muscle fatigue

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3
Q

How much respiratory work does the diaphragm do?

A

75%

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4
Q

What is the relationship between alveolus size and collapsing pressure?

A

As the alveolus size increases the collapsing pressure decreases

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5
Q

What does elastic recoil of the lungs want to do?

A

Collapse lungs

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6
Q

What does elastic recoil of the chest wall want to do?

A

Expand lungs

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7
Q

What do the elastic recoil of the lungs and chest wall do?

A

Balance eachother out at the FRC line

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8
Q

Pneumothorax

A

Puncture of lung causes atmospheric pressure to rush in and causes collapse of lungs

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9
Q

What does lung compliance reflect?

A

How easily the lung is distended

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10
Q

Type 1 alveolar cells

A

Cover most of the alveolar wall

Thin cell thickness and flat (squamous) which allow gas exchange

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11
Q

Type 2 alveolar cells

A

Plump in size, when stretched secrete surfactant a material that forms a film and reduces surface tension

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12
Q

What does surfactant make easy?

A

The alveoli to inflate even if they collapse

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13
Q

How does surfactant reduce surface tension?

A

By decreasing density of water molecules

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14
Q

What does surfactant allow the alveolus to do?

A

Have low collapsing pressure even at small sizes

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15
Q

What are the primary roles of the surfactant?

A

Reduce work of breathing by decreasing surface tension forces

Prevent collapse and sticking of alveoli on exhalation

Keeps alveolar size relatively uniform

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16
Q

What is surfactant inactivated by?

A

Hypoxia

Infection

Edema fluid (due to decreased lung compliance)

17
Q

Emphysema

A

Loss of elastic fibers so lung compliance increases

18
Q

How do patients with emphysema breathe?

A

At higher lung volumes (higher FRC)

19
Q

Fibrosis

A

Stiffening and decreased compliance (lower FRC)