Hormones

Question 1

what is the principle of cell signaling in the correct order?

Answer 1

reception, transduction, response

Question 2

T/F: Protein hormones, steroid hormones, and catecholamines are unable to diffuse into the cell.

Answer 2

false

Question 3

What hormone do leydig cells produce when stimulated by LH?

Answer 3

testosterone

Question 4

Describe the basis of hormonal signaling, the three basic terms and how they enter the blood stream

Answer 4

all hormones are released into the blood stream, but only certain receptors will receive them
-reception, transduction, response

Question 5

describe all the details of peptide hormone, synthesized, how it affects the cell

Answer 5

-synthesized on the rough ER
-Stored in vesicles
-acts through secondary message system
-leave cell via exocytosis
-contains a lipid bilayer/ soluble in aqueous solutions
HYDROPHILLIC: can’t cross the target cell membrane
-binds to transmembrane receptors( g proteins)
—- rapid affects on the target system

Question 6

describe all the details of steroid hormones

Answer 6

• derived from cholesterol
  -not water soluble
  -HYDOPHOBIC
  -can pass though plasma membrane
  -can’t be stored in the cell
  -fast response: G protein/ outside the cell
  -slow response: binding to receptor in the interstitial fluid, inside the cells
  -no second msg center

Question 7

Name the 4 cell surface receptors

Answer 7

g protein coupled receptor, ion-channel receptors, tyrosine kinase linked receptors, receptors w/ intrinsic enzymatic activity

Question 8

what is an agonists and antagonists?

Answer 8

agonists: activate receptors/ response
antagonists: block receptors (no response)

Question 9

describe the following definitions, receiver, transducer, amplifier,
responder

Answer 9

receiver: ligand binding receptor
transducer: conformational change of receptor
amplifier: signal transduction, pathway increases the number of molecules affected
responder: something that is responding to signal

Question 10

What is the role of intracellular receptors?

Answer 10

regulate transcription of target genes by binding to specific DNA sequences/ increases or decreases mRNA production