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Farma Biocontroladores > Hormonas Masculinas > Flashcards

Hormonas Masculinas Flashcards

1
Q

Indicaciones para analogos de la testosterona

A

Hipogonadismo

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2
Q

Efectos adversos de Analogos de la Testosterona

A
  • Acne
  • Edema
  • ↑ Hematocrito
  • Cambios de humor, irritabiliad, fatiga
  • Insomnio
  • ↑ concentrciones sericas de Estradiol
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3
Q

Antagonistas de Receptores de Androgenos

A
  • Biclutamida
  • Flutamida
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4
Q

Tamsulosina

A

Bloqueador a1 sletivo

Simpaticolitico

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5
Q

Tx para Hiperplasia Prostatica Benigna

A
  • Tamsulosina (Bloqueado a1 selectivo)
  • Finasterida (inhibidor de 5a-reductasa)
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6
Q

MOA de Tamsulosina

A

Bloqueador a1 selectivo

relja el musculo liso del cuello de la vejiga y uretra → ↓ resistencia al flujo urinario

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7
Q

Efectos adversos de Tamsulosina

A
  • Hipotensión ortostatica
  • Eyaculación retrograda (por relajación de los musc. de la vejiga)
  • Edema
  • Mareos, Cefalea
  • Sindrome del iris flacido inatraoperatorio → desprendimiento de la retina y endoftalmitis
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8
Q

Hormona masculina que puede causar Eyculación Retrograda

A

Tamsulosina

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9
Q

Hormona masculina que puede causar el desprendimiento de la retina y endoftalmitis

A

Tamsulosina

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10
Q

Inhibidor de la 5a-reductasa

A

Finasterida

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11
Q

Hormona masculina que ↓ volumen de la prostata y ↓ riesgo de retención urinaria

A

Finasterida

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12
Q

Efectos adversos de Finasterida (inhibidor de 5a-reductasa)

A
  • Disfuncion sexual
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13
Q

5a-reductasa convierte Testosterona → ___

A

Dihidrotestosterona

la cual actua en los receptores de androgenos

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14
Q

Hormona Masculina que ↓ los niveles intraprostaticos de DHT (dihidrotestosterona)

A

Finasterida

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15
Q

Inhibidor de PDE5

A

Sildenafil (Viagra)

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16
Q

MAO de Sildenafil (Viagra)

A

relajación del musc. liso en reacción al Oxido Nitrico → Vasodilatación

17
Q

Tx de Disfuncion Erectil

A

Sildenafil (Viagra)

18
Q

Viagra _ el musc. liso del pene

A

Relaja

19
Q

Efectos adversos de Viagra

A

Efectos Cardiacos (ej. IAM)

20
Q

Tx de Vejiga hiperactiva y neurogenica

A

Tolterodina

21
Q

MOA de Telterodina

A

Antagonista de receptor muscarinico

22
Q

Tx para px con cancer de prostata metastico resisente a hormonas

A

Estramustatina

= agente citotoxico

Farma Biocontroladores (14 decks)

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