Homestasis- Topic 6C Flashcards
What is Negative feedback
The change produced by a system to restore systems to their original level.
What is Glycogenisis
blood glucose conc too high so liver produces enzymes that mean glucose converted into glycogen (stored in liver cells)
genesis means to make
What is Glycogenolysis?
When blood glucose concentration is too low ezymes in liver break down glycogen into glucose
lysis means to breakdown
What is the importance of maintaining a stable core temperature and stable blood pH?
So cells can function normally and stop them being damaged. -e.g. enzymes being denatured
Glucose is needed for ………, so a lack of glucose in the blood could result in …. …….
respiration, cell death
When will blood glucose increase and decrease?
following ingestion of food or drink containing carbohydrates and will fall following exercise or if you have not eaten
What two things change the concentration of glucose in your blood?
Eating and Exercise
Name the 2 hormones responsible for controlling glucose concentration
Insulin
Glucagon
What is the role of beta cells?
to secrete insulin into the blood
What is the role of alpha cells?
to secrete glucagon into the blood
Describe how blood glucose concentrations are lowered when it’s too high
insulin binds to specific receptors on surfaces of target cells
increases the permeability of muscle-cell membranes to glucose ( MORE TRANSPORT PROTEINS) so cells can take in more glucose (inc the number of channel proteins)
insulin activates enzymes in liver and muscle cells to convert glucose to glycogen (glycogenesis)
Describe how blood glucose concentrations are increased when it’s too low
Binds to specific receptors on cell membranes of liver cells
activates enzymes in liver cells that breaks down glycogen into glucose (glycogenolysis)
also activates enzymes involved in formation of glucose from glycerol and amino acids (gluconeogenesis)
What is gluconeogenesis?
The formation of glucose from glycerol and amino acids
The role of adrenaline
secreted when low conc of blood glucose in your blood.
makes more glucose available for muscles to respire
How adrenaline works…
binds to receptors on membrane of liver cells
activates glycogenolysis
inhibits glycogenesis
activates glucagon secretion and inhibits insulin secretion