Homeostatis, body fluids and oedema Flashcards
Define homeostatus
homeo = sameness and status = standing still
what needs to be maintained constant internal environment
water, temperature and pH
How do you maintain homeostatus
Positive and negative feedback loops
Negative feedback loops four parts
- Stimulus
- Sensor
- Control
- Effector
What happens we are too hot
Vasodilation
sweating
Pilorelaxtation
stretching out
What happens when your to cold
Vasoconstriction
shivering
piloerection
curling up
Describe the negative feedback loop of eating food
Eating food increases blood glucose pancreas beta cells release insulin Labour obtains glucose and stores as glycogen Blood glucose levels decrease system turned off
Positive feedback system of blood clotting
Platelets release chemicals which recruit more platelets which activates more platelets
Positive feedback labour example
The baby’s head pushing and cervix causing stretching
Stretching of the cervix causes nerve impulse to be sent to the brain
the brain stimulates the posterior pituitary to release oxytocin
oxytocin cause the uterus to contract, hence further pushes head into the uterus
Core body temperature defined as
Temperature of head and thorax
Where we can use themometer
Auditory oral temporal axillary Bristol
Normal pH range
7.35-7.45
Two major organs responsible for maintaining the acid-base balance are
The Lungs respiratory balance
the kidneys metabolic balance
Lungs and respiratory balance
H+ + HCO3- <=> H2CO3 <=> (Carbonic Anhydrase) H20 + CO2
Kidneys metabolic balance
Kidneys can excrete or retain H+ OR HCO3-
Alot more powerful than respiratory compensation
PH have gut
1.5-3.5
PH
ph=-log10[H+]
Changes in hydrogen iron concentration need significant changes in pH
How to measure blood gas analysis
Use radiometre
Palace water split into compartments
60% water
2/3 intracellular fluid and 1/3 extracellular fluid
this 1/3 80% interstitial fluid and 20% plasma
Total body water in male female infants
male female infant
normal 60 50 70
lean 70 60 80
obese 50 42 60
Hypertonic
hypotonic
Cell inflates, high osmolarity
so shrinks, close polarity
Transmembrane protein for the book movement of water
auqaporins
Osmolarity vs osmolality
milliosmoles per L
milliosmoles per Kg (Clinical way use because does not rely on temperature or pressure)
Oedema is
Fluid retention hydrostatic pressure> onconic pressure
For causes of oedema
- Raise hydrostatic pressure in capillary
- Decreased onconic pressure in the capillary - Live disease low albumin
- Increase onconic pressure in the interstitium - increased vascular permeability in inflamation - leakage of plasma proteins
- Impaired lymphatic drainage (lymphoedema) - Presence of puzzle proteins in the interstitial fluid lymphatics blocks or damage