Glands introduction Flashcards

1
Q

Definition of a gland

A

An epithelial cell or an aggregate of epithelial cells that are specialised for the secretion of a substance

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2
Q

Defines secretion

A

The production and release of material by a cell or aggregate ourselves

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3
Q

How a glans classififed

A
  1. The structure

2. How their products are released

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4
Q

Define Endocrine

A

Secrete directly into the blood to act on distal parts of the body. Secretions called hormones

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5
Q

3 examples of Endocrine glands

A

pituitary
thyroid
parathyroid

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6
Q

What is the anterior pituitary release

A

ACTH
luteinising hormone
follicle-stimulating hormone
thyroid stimulating hormone
prolactin - stimulates milk production in mothers
somatotrophin - a hormone which regulates the growth of the body and tissue

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7
Q

What does the posterior pituitary release

A

Antidiuretic hormone - prevents water loss from kidneys

oxytocin - signal uterus for delivery of baby

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8
Q

Thyroid glands release

A

T3 active and T4 inactive

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9
Q

Parathyroid gland release

A

Parathyroid hormone, calcium homeostasis

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10
Q

What epithelial cells of a Endocrine tissue secrete substance

A

All epithelial cells secrete the hormones in the gland

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11
Q

Define exocrine

A

Glands secrete into a location or region of the body through a duct and the secretion is mostly enzymes or lubricants

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12
Q

Give six examples of endocrine glands

A
Salivary gland
pancreas
mammary
sweat gland
sebaceous glands
lachrymal glands
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13
Q

Salivary gland

A

Secrete saliva, function includes partial digestion of food and lubrication

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14
Q

Pancreas

A

enzymes: amylase trypsin and lipase these enzymes digest carbohydrates proteins and fats respectivly

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15
Q

Mammary glands

A

Produce milk in response to prolactin and oxytocin

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16
Q

Sweat glands

A

Screech sweat which regulates body temperature

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17
Q

Sebaceous glands

A

Secrete sebum onto the skin of the ear protectors you from pathogen

18
Q

Lachymal glands

A

In I secretes water to moisten the eye also produces lysosomes

19
Q

In exocrine glands what cell releases product

A

Only apex of ducted secretes product

20
Q

In exocrine glands what cell releases product

A

Only apex of duct secretes product

21
Q

In lungs branch and occurs by growth factor 1 and 2 explain how we get trivial elongation or tubule branching

A

Elongation factor one active growth and two in active

branching growth up to one in active growth factor to active

22
Q

Some cells are end of ducks change morphology explain this

A

Myoepithelial cells - cells that have features of both epithelial cells and smooth muscle cells - helps injecting secretions from the duct

23
Q

Three types of secretions

A

Merocrine
apocrine
holocrine

24
Q

merocrine

A

vesicles fuse with membrane cargo released outside by exocytosis. Two pathways regulated and constitutive

25
Q

apocrine

A

Partial loss of cytoplasm. vesicles bundle at top of cell whole top of cell is released

26
Q

holocrine

A

Complete loss of cytoplasm also

27
Q

How is secretion controlled

A

Negative feedback
nervous
endocrine
neuroendocrine

28
Q

Explain merocrine regulated and constitutive regulation

A

Regulated: secretory granules accumulate in large be schools and are released by exocytosis upon stimulation, need calcium ions

constititive: the secretory product is not concentrated into granules but packaged into small the schools and continues to be released to he cell surface - use may need to repopulate the plasma membranes

29
Q

Merocrine pathway release of insulin from beta cells of the pancreas

A

Glucose moves into cell viaGLUT2
potassium channels open allowing potassium to leave cell
this Depolarises the cell
causes voltage-gated calcium channels to open
calcium used in these confusion causes insulin released outside cell

30
Q

Give an example of an Apocrine secretion

A

Breast - both fat and milk realised this way

31
Q

holocrine example

A

Sebaceous gland
the secretory cell fills up with secretory granules
cells organelles die
the cells die
the plasma membrane breaks and the contents released
dead cells are replaced by mitotic division in the basal cells

32
Q

Role of Golgi apparatus

A

Secretion of proteins

glycosylation of proteins

33
Q

Where does Golgi apparatus glycosylation occur

A

Trans-Golgi

34
Q

Why glycosylated proteins

A

Aid folding
prevent digestion
cell ecognition e.g. blood groups
roll on cell to extracellular matrix attachment

35
Q

Exocytosis vs endocytosis

A

Exocytosis
secretion of molecules outside the cell by vesicle fussing to a membrane

Endocytosis
engulfing of molecules inside the via vesicle formation

36
Q

Two types of endocytosis

A

Phagocytosis- engulf other cells

Pinocytosis- cell drinking

37
Q

Trans-epithelial transport

A

Passive diffusion
through Lipid membrane
transported by carrier proteins
or impermeable proteins could be transported by Endo and exocytosis

38
Q

Control gland secretions

A

Hormonal, neural, humoral

39
Q

neural

A

Release of hormones in response to nerval stimulus

40
Q

humoral

A

Control of hormone release in response to changes in the extracellular fluid levels or ion levels

41
Q

neurocrine

A

Example the hypothalamus to the pituitary