Bone and cartilage Flashcards

1
Q

Three types of cartilage

A

Hyaline
elastic
fibrocartilage

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2
Q

Four types of collagen

A

type one: tendons, dermis, bones
type II: hyaline cartilage
type III: reticulin
type iv: basal lamina

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3
Q

What things do all the types of cartilage have

A

All have chondrocytes

all have a matrix containing glucoaminoglycans and hyaluronic acid

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4
Q

What is meant by a vascular cartilage

A

No blood vessels

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5
Q

How do you get chondrocytes

A

mesenchymal stem cells
chondroblasts when differentiated
chondrocytes were entrapped in Lucunae

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6
Q

How do chondrocytes laydown extracellular matrix

A

By vesicles

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7
Q

Does hyaline cartilage contain a Perivhondrium

A

Yes

however not present on articulating surfaces

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8
Q

Chondrocytes are present singularly or in groups explain

A

Small clusters called I suggest groups, separate from each other when chondrocytes start laying down extrasolar matrix

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9
Q

As long brains develop some hyaline cartilage remains in two areas

A

Articulating surfaces

epiphysis plates

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10
Q

Where can hyaline cartilage be found

A

Trachea

nose articulating joints

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11
Q

perichondrium is made up of

A

Dense connective tissue

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12
Q

2 types of growth in hyaline cartilage are

A

Grew from periphery= appositional growth

growth from centre= interstitial growth

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13
Q

Elastic cartilage made up of what kind of collagen

A

2

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14
Q

As elastic collagen contain perichondrium

A

Yes

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15
Q

Where can elastic collagen be found

A

Pinna of the year

epiglottis

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16
Q

Fibre cartilage type of collagen it contains

A

Type of collagen it contains Type one and type II

17
Q

Does fibre collagen contain perichondrium

A

No

18
Q

Where is fibro collagen found

A

Intervertebral discs

19
Q

endochondrial ossification occurs in what bones

A

Long bones

20
Q

What is the collar of bone first seen during endochondral ossification called

A

Periosteal a.k.a. compact bone

21
Q

During endochondral ossification nutrient artery does what

A

Calcified cartilage supplies blood depositing osteogenic cells

22
Q

During endochandrail ossification the Medulla calcifies to what kind of bone

A

Cancellous bone

23
Q

When osteoblast become osteocytes they change phenotype

A

Send out filiopodia to communicate with other osteocytes

24
Q

Osteoarthritis

A

Age-related
mechanical failure of the articular cartilage a.k.a. hyaline
narrowing of the joint space bones rub against bone

25
Q

Rheumatoid arthritis

A
Autoimmune
inflammation of the synovial membrane
thickening of the joint capsule
subsequent damage to underlying bone and articulating cartilage
bone and cartilage breakdown