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step 1 immunology > HLA Subtypes associated with diseases > Flashcards

HLA Subtypes associated with diseases Flashcards

1
Q

A3

A

Hemochromatosis

locus LINKED to causative mutant gene, HFE

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2
Q

B8

A

Addison’s disease

myasthenia gravis

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3
Q

B27

A 
Seronegative Arthropathies:
Psoriatic arthritis
Ankylosing spondylitis
IBD-associated arthritis
Reactive arthritis (aka Reiter's syndrome)

“PAIR”

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4
Q

DQ2

A

Celiac’s disease

I 8 2 much gluten at DQ

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5
Q

DQ8

A

Celiac’s disease

I 8 2 much gluten at DQ

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6
Q

DR2

A

MS
hay fever
SLE
Goodpasture syndrome

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7
Q

DR3

A 
DM Type 1
SLE
Grave's Disease
Hashimoto thyroiditis
Addison's disease
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8
Q

DR4

A

Rheumatoid Arthritis
DM Type 1
Addison’s disease

(4 walls in the “rheum”)

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9
Q

DR5

A

Pernicious Anemia

Hashimoto thyroiditis

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step 1 immunology (13 decks)

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