HLA Subtypes associated with diseases Flashcards
1
Q
A3
A
Hemochromatosis
locus LINKED to causative mutant gene, HFE
2
Q
B8
A
Addison’s disease
myasthenia gravis
3
Q
B27
A
Seronegative Arthropathies: Psoriatic arthritis Ankylosing spondylitis IBD-associated arthritis Reactive arthritis (aka Reiter's syndrome)
“PAIR”
4
Q
DQ2
A
Celiac’s disease
I 8 2 much gluten at DQ
5
Q
DQ8
A
Celiac’s disease
I 8 2 much gluten at DQ
6
Q
DR2
A
MS
hay fever
SLE
Goodpasture syndrome
7
Q
DR3
A
DM Type 1 SLE Grave's Disease Hashimoto thyroiditis Addison's disease
8
Q
DR4
A
Rheumatoid Arthritis
DM Type 1
Addison’s disease
(4 walls in the “rheum”)
9
Q
DR5
A
Pernicious Anemia
Hashimoto thyroiditis