Autoantibodies Flashcards

1
Q

Anti-ACh receptor

A

myasthenia gravis

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2
Q

myasthenia gravis

A

Anti-ACh receptor

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3
Q

Anti-basement membrane

A

Goodpasture syndrome

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4
Q

Goodpasture syndrome

A

Anti-basement membrane

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5
Q

Anticardiolipin

A

SLE, antiphospholipid syndrome

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6
Q

Lupus anticoagulant

A

SLE, antiphospholipid syndrome

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7
Q

SLE, antiphospholipid syndrome

A

Anticardiolipin, lupus anticoagulant

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8
Q

Antidesmoglein

A

Pemphigus vulgaris

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9
Q

Anti-dsDNA

A

SLE

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10
Q

Anti-Smith

A

SLE

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11
Q

SLE

A

Anti-dsDNA, anti-smith, anticardiolipin, lupus anticoagulant, ANA

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12
Q

Anti-GAD 65

A

DM Type 1

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13
Q

DM Type 1

A

Anti-GAD 65

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14
Q

Antihemidesmosome

A

Bullous pemphigoid

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15
Q

Bullous pemphigoid

A

Antihemidesmosome

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16
Q

Anti-histone

A

Drug induced lupus

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17
Q

Drug induced lupus

A

Anti-histone

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18
Q

Anti-Jo-1, Anti-SRP, Anti-Mi-2

A

Polymyositis, dermatomyositis

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19
Q

Polymyositis, dermatomyositis

A

Anti-Jo-1, Anti-SRP, Anti-Mi-2

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20
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto’s thyroiditis

21
Q

Hashimoto’s thyroiditis

A

Antimicrosomal, antithyroglobulin

22
Q

Antimitochondrial

A

Primary biliary cirrhosis

23
Q

Primary biliary cirrhosis

A

Antimitochondrial

24
Q

Anti-parietal cell

A

Pernicious anemia

25
Q

Pernicious anemia

A

Anti-parietal cell

26
Q

Anti-phospholipase A2 receptor

A

Primary membranous nephropathy

27
Q

Primary membranous nephropathy

A

Anti-phospholipase A2 receptor

28
Q

Anti-DNA topoisomerase I

A

Scleroderma (diffuse)

29
Q

Scleroderma (diffuse)

A

Anti-DNA topoisomerase I

30
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

31
Q

Autoimmune hepatitis type 1

A

Anti-smooth muscle

32
Q

Anti-SSA, Anti-SSB

A

Sjogren Syndrome

33
Q

Sjogren Syndrome

A

Anti-SSA, anti-SSB

34
Q

Anti-TSH receptor

A

Graves disease

35
Q

Graves disease

A

Anti-TSH receptor

36
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

37
Q

Mixed connective tissue disease

A

Anti-U1 RNP (ribonucleoprotein)

38
Q

Anti-VGCC

A

Lambert-Eaton syndrome

39
Q

Lambert-Eaton syndrome

A

Anti-VGCC

40
Q

IgA anti-tissue transglutaminase

A

Celiac disease

41
Q

Celiac disease

A

IgA anti-tissue transglutaminase

42
Q

MPO-ANCA, p-ANCA

A

Microscopic polyangiitis, Churg-Strauss Syndrome

43
Q

Microscopic polyangiitis, Churg-Strauss Syndrome

A

MPO-ANCA, p-ANCA

44
Q

PR3-ANCA, c-ANCA

A

Granulomatosis with polyangiitis (aka Wegener’s)

45
Q

Granulomatosis with polyangiitis (aka Wegener’s)

A

PR3-ANCA, c-ANCA

46
Q

What is RF?

A

IgM Anti-IgG Fc

47
Q

RF, anti-CCP

A

Rheumatoid Arthritis

48
Q

Rheumatoid Arthritis

A

RF, anti-CCP