HIV - Infections Flashcards
DOC for PCP
Bactrim
DOC for aspergillosis
Voriconazole or amphoB
DOC for candidiasis
Fluconazole
DOC for coccidioidomycosis
fluconazole, itraconazole, amphoB
DOC for cryptococcal
AmphoB, fluconazole, flucytosine, itraconazole
DOC for histoplasmosis
Itraconazole, amphoB
DOC for toxoplasmosis
Meningitis
PCP
SX
PPX
TX
Alternative
Fever, dry cough, SOB, night sweats
Bactrim 1t PO QD when CD4 <200
Bactrim 2T PO QD + prednisone x 21 days
Dapsone or atovaquone
Toxoplasmosis
When to start
PPX
TX
CD4 <100
Bactrim 1T PO QD
Sulfadiazine + Pyrimethamine + leucovorin
What can cause bacterial diarrhea in AIDS?
Salmonella
Campylobacter jejuni
Shigella
MAC
Sx
PPX
Cough, fever, night sweats, hempotysis
Not recommended if the are on ART
PPX indicated if not on fully suppressive ART and CD4 <50 then give
Clarithromycin 500mg PO BID or azithromycine 1200mg PO weekly
CMV
Complications
Treatment
Curable?
CMV retinitis causing permanent blindness
oral valganciclovir
If sight threatening lesions - give intravitreal ganciclovir
Which latent tuberculosis regiment is preferred in HIV patients?
Isoniazid 300mg + pyridoxine 50mg QD x 9 months
Tesamoreline
Brand
Indication
MOA
Dose
Contraindication
Egrifta
HIV-associated lypodystrophy
GRF analoge
2mg SC QD
Preganant, active malignancies
Metreleptin
Brand
Indication
MOA
Dose
Myalept
Lipodystrophy
Human leptin analog
SUBQ
REMS required
Crofelemer
Brand
Indication
Dose
Mytesi
Anti-diarrheal for HIV/AIDS patients on ART
125mg BID PO