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Med Science Term 1 > History Of Pharmacology > Flashcards

History Of Pharmacology Flashcards

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1
Q

Pharmacology

A

Studying effects ofdrugs on function on living systems

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2
Q

Drug

A

Chemical substance known structure which is administrated to a living organism, produces a biological effect

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3
Q

Medicine

A

Chemical preparation administrated with intention of producing a therapeutic effect

Will contain the drug

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4
Q

Modern biomed pharmacology

A

Developed mid 1800s

Chemistry
Physiology
Pathology

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5
Q

Egyptians

A

EBERS papyrus 1550BC

ancient text of medicine

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6
Q

Greeks

A

40-90AD

Pedanius Dioscorides

De Materia Medica
Medicines and plants

1st pharmacopeia

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7
Q

Fathers of pharmacology

A

Rudolph Buccheim

Oswald Schmiedeberg

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8
Q

Rudolph Buccheim

A

1st professor pharmacology 1847

Drug mode of action
This developed understanding of drugs and doses etc

Experimental pharmacology to investigate

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9
Q

Oswald Schmiedeberg

A

Buccheim student

Studied chloroform
Published outline of pharamacology
Defined modern pharmacology

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10
Q

Why feel pain

A

Warns us of actual or potential tissue damage

Encourages us to withdraw. Lib/tissue to aid healing

Protect to aid healing

Learn from experience

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11
Q

Early pain relief

A

Spiritual
Humoral balance

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12
Q

Humoral balance

A

4 fluid components:

Blood
Phelgm - water
Yellow bile -liver
Black bile - gall bladder

So primitive and uncontrolled

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13
Q

Opium in early days

A

Poppy plant
Egypt to Greece to Europe
In ebers papyrus and de material medica

Pain relief, sponging surgical wounds, sleep inducing, euthanasia, soothing crying child, calming disturbed individuals

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14
Q

Non refined extract of poppy plant dissolved in alcohol

A

Tincture of opium

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15
Q

Isolating morphine

A

1804 Freidrich Sertumer Germany from tincture

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16
Q

Morphine

A

Most abundant active component of opium extract

1st isolated active ingredient for any drug

Marketed by serturner 1817 as analgesic and alcohol n opium addiction

Children and soldiers

17
Q

Intravenous morphine

A

Using hypodermic needle

Much more potent

18
Q

Morphine today

A

Effective painkiller
Intravenous easy and efffects almost instantaneous

19
Q

Heroin

A

Semi synthetic

More potent n addictive
Intravenous

20
Q

Drug targets

A

Specific of a drug to a target

Receptors
Enzymes
Carrier molecules
Ion channels

Stimulate or inhibit

Med Science Term 1 (19 decks)

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