Addiction Flashcards
Addiction dependent
Drug taking compulsive
More important than other knock on consequences
Physical & psychological dependent
Drug abuse
Recurrent use
Pleasure seeking
Can develop into addiction
Drug tolerance
Decrease pharmacological effects with repeated use
Need to increase dose
Accompanies addiction
Withdrawal syndrome
Adverse physical psychological effects when stop taking
Days months, years
History addiction
Mushrooms
Frogs toad venom
Cojobano seeds
Alcohol
Opium
Morphine & heroin
Hedonic drugs
Pleasure
Reward mechanism
Reinforce basic survival behavieur
Reward pathway
Mesolimbic or pleasure pathway
Releases dopamine
Activates cerebral cortex, cerebellum and spinal cord
Control of reward pathway
Pleasure kept down by inhibitory inputs
activates pleasure pathway
Drugs inhibit or stimulate
Withdrawalsyndrome
Physical:
Down regulation reward pathway
Physiological:
Brain learned to connect drug with reward
Craving
Stimulated by association
Addiction treatment long & short
Short term:
Methadone - opined
Diazepam-alcohol
Long:
Gradually & progressively reduce drug dose
Contracted prescribed form
Restabish natural balance
Addiction treatment: blocking aversion
Blocking:
Prevent effect
Blacking drug target
Prevent relapse
When addict making good progress
Aversion:
Unpleasant response to drug
Discorage relapse
Addiction treatment:psychological therapy
Helps unlearn drug taking behaviour
Helps long lasting psychological dependence
