Histology pt 2 Flashcards

1
Q

Connective tissue

A

Consists of cells and extracellular matrix

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2
Q

Extracellular matrix

A

3-dimension network consisting of extracellular molecules and minerals such as proteins, glycoproteins, proteoglycans, minerals and hydroxyapatite providing structural and biochemical support to surrounding cells and tissue.

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3
Q

Non fibrous components

A

Ground substance
Glycosaminoglycans
Glycoproteins and proteoglycans

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4
Q

Ground substance

A

Amorphous gel-like substance in extracellular space. Composed of water and large organic molecules. Involved in movement of tissues and metabolism. Provides lubrication for fibrous component of ECM

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5
Q

Glycosaminoglycans

A

polysaccharides that trap water, giving the ground substance a gel-like texture

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6
Q

Glycoproteins and proteoglycans

A

modified proteins that have oligosaccharide or polysaccharides attachments. Give ground substance structure

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7
Q

Areolar tissue structure

A

loose, fluid-like
Allows movement of cells - ^GS

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8
Q

Tendon structure

A

Dense
Providing strength
Decreased GS

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9
Q

Collagen fibres

A

long and unbranched, flexible and provide strength to tissue

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10
Q

Reticular fibres - collagen and function

A

Consist of collagen but are thinner and branched, forming a strong but flexible structure

Found in organs where they provide structure to the organ but allow movement of cells

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11
Q

Elastic fibers

A

Made up of elastin and are branched and allow tissue to stretch up to 200% original shape

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12
Q

Loose connective tissue - Areolar

A

-Thin collagen fibres
- Reticular fibres
- Elastin fibres

Holds organs in place and provides cushioning. Attaches epithelial tissue to underlying tissue and allows cell movement e.g phagocytic cells which provide defense against pathogens

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13
Q

Loose connective tissue - Adipose tissue

A

-Reticular tissue
- Collagen III
-High GS

Provides cushioning, insulation; stores energy.

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14
Q

Obesity in cells

A

increased GS which leads to increased PG. PG bind to inflammatory/immune cells and increase inflammation which leads to a metabolic disease

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15
Q

Loose connective tissue - Reticular

A

Collagen III
Increased GS

Fibres from a supporting skeleton for organs and allows movement of cells and fluids

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16
Q

Dense connective tissue - dense regular

A

Collagen I
1-2% elastin
decreased GS

Provides firm attachment, provides strength

17
Q

Dense connective tissue - dense irregular

A

Collagen I
2-4% elastin
decreased GS

Provides strength, resistant to forces from different directions

18
Q

Hyaline cartilage

A

Collagen II
- fibrous network that holds the GS
- increased PG, glycoproteins and water

Reduces friction, allows for compression, provide flexible support

19
Q

Elastic cartilage

A

Collagen II
Elastin
Decreased GS

Provides support and flexibility, allows tissue to distort but return to original shape

20
Q

Fibrocartilage

A

Collagen I & II
Decreased GS

Resists compression, provides cushioning

21
Q

Bone

A

ECM made up of hydroxyapatite and collagen.

Hydroxyapatite - strong by inflexible, can withstand compression but not bending, twisting

Collagen - tolerated bending and stretching but not compression, provide a framework for the formation of hydroxyapatite crystals

22
Q

Canaliculi function

A

Produce ECM molecules

23
Q

Compact bone

A

Made of osteons. Protection and strength

24
Q

Spongy bone

A

Made up of trabeculae, save weight

25
Q

Woven bone

A

Fibrous bone
Haphazard arrangement of collagen and is weak unlike the lamellae of osteon or trabeculae. Formed during development and replaced by lamellar bone

26
Q

Collagen III is in

A

Reticular and adipose tissue

27
Q

Collagen II is in

A

Hyaline cartilage, articular cartilage and fibrocartilage

28
Q

Collagen I is in

A

Dense irregular, dense regular and fibrocartilage