Histology of the female reproductive organs Flashcards
What are the two distinct histologic regions of the ovary?
Cortex and medulla
In which of the two distinct histologic regions of the ovary are the ovarian follicles located?
Cortex
In which of the two distinct histologic regions of the ovary are blood vessels, lymphatic vessels and nerves located?
Medulla
The tunica albuginea lies between which layers?
Germinal epithelium and cirtex of the ovary
What are the three basic histological types of ovarian follicles?
Primordial follicles, growing follicles, mature/Graafian follicles
When does the primordial follicle first appear in the ovaries?
Third month of fetal development
Early growth of the primordial follicle is (dependent/independent) of gonadrotropin stimulation.
Independent
What is an ooplasm?
The cytoplasm of an oocyte
Which is the first stage in the development of a growing follicle: primary oocyte or primordial oocyte?
Primary oocyte
What type of cells surround the primordial oocyte?
A single layer of squamous follicle cells
The outer surface of the follicle cells is surrounded by a basal lamina. T/F
T
What type of cells surround the primary oocyte?
A single layer of cuboidal follicular cells
The primary oocyte secretes specific proteins that are assembled into an extracellular coat called what?
Zona pellucida
The zona pellucida is between which layers of cells?
Between the primary oocyte and follicular cells
Where does the granulosa layer of the primary follicle come from?
Mitosis of follicular cells
Which type of cell junctions develop between granular cells of the orimary follicle?
Gap junctions
Which cells surround the follicle to form a sheath of connective tissue cells called theca folliculi?
Stromal cells
The theca folliculi is external the basal lamina of follicle cells. T/F
T
Theca folliculi differentiates into which two layers?
Theca interna and theca externa
Which layer of the theca folliculi is highly vascularized?
Theca interna
Which layer of the theca folliculi consists mainly of smooth muscle cells and bundles if collagen fibers?
Theca externa
Which layer of the theca folliculi consists of secretory cuboidal cells?
Theca interna
The granulosa layer is (vascukar/avascular) during follicular growth.
Avascular
The stratum granulosum reaches the size of how thick before fluid-filled cavities appear?
6 to 12 cell layers
The secondary follicle is characterized by which structure?
Antrum, a fluid-filled cresent shaped cavity
What is the thickened mound of granulosa cells projecting into the antrum?
Cumulus oophorus
The cells of the cumulus oophorus that immediately surround the oocyte and remain with it is called what?
Corona radiata
Which type follicle contains the secondary oocyte?
Mature follicle or Graafian follicle
In the mature follicle, which is thicker: antrum or stratum granulosum?
Antrum
What is ovulation?
A hormone mediated process resulting in the release of the secondary oocyte from the Graafian follicle.
The corpus luteum comes from what structure?
The follicular wall - remaining granulosa and thecal cells
What are the three layers of the uterine tubes?
Serosa, muscularis, mucosa
The wall of the uterine tubes resemble the wall of other hollow viscera except for the absence of which layer?
Submucosa
What is the type of cells that line the mucosa of the uterine tubes?
Simple columnar epithelium - ciliated and non-cilliated
Ciliated columnar epitheliuum is more numerous in which part of the uterine tubes?
Infundibulum and ampulla
The wave of the cilia of the mucosal cells in the infundibuluma and ampulla is towarxs which direction?
Towards the uterus
What is the function of noncilliated peg cells of the mucosal lining of the uterine tubes?
Secretion of fluid that provides nutritive material for the ovum
Epithelial cells of the uterine tubes hypertrophy during (follicular phase/luteal phase).
Follicular phase
Epithelial cells of the uterine tubes (hypertrophy/atrophy) during the luteal phase.
Atrophy
Which layer/s of the uterus undergo changes in the menstrual cycle?
Myometrium and endometrium
Which is the thickest layer of the uterus?
Myometrium
What are the three smooth muscle layers of the myometrium?
Stratum vasculare, and inner and outer layers
During reproductive life, the endometrium consists of which two layers?
Stratum functionale and stratum basale
Which layer of the endometrium is the thick part that is sloughed off at menstration?
Stratum functionale
Which layer of the endometrium is retained during menstration?
Stratum basale
Which blood vessels of the uterus undergo degeneration and regeneration under the influence of estogen and progesterone in each menstrual cycle?
Distal portion of the spiral arteries
The cervical mucosa contains large, branched glands that are not in the endometrium. T/F
T
The cervical mucosa has no spiral arteries. T/F
T
The portion of the cervix that projects into the vagina is called what?
Ectocervix
What type of cells cover the ectocervix?
Stratified squamous epithelium
What type of cells cover the endocervix?
Columnar epithelium
What are the three layers of the vaginal wall?
Mucosal layer, muscular layer, adventitial layer
The mucosal layer of the vagina is covered with what type of cells?
Stratified squamous epithelium
The mucosal layer of the vagina has numerous rugae. T/F
T
The muscle layer of the vagina consists of which layers?
An outer longitudinal smooth muscle, an inner circular muscle
Which muscular layer of the vagina is thicker: outer longitudinal or inner circular?
Outer longitudinal
The outer longitudinal layer of the vagina is continuous with the corresponding layer of the uterus. T/F
T
The adventitial layer of the vagina is organized into which two layers?
Inner dense CT layer, outer loose CT layer
The inner adventitial layer of the vagina contains which type of fibers?
Elastic fibers
Which layer of the vaginal adventita contains blood vessels, lymphatics and nerves?
Outer loose CT layer
The surface of the vagina is lubricated by the secretions of its glands. T/F
F
Glands are not present in the vaginal wall. Cervical and vestibular secretions lubricate the vagina.
The lamina propria of the vagina has an outer layer that is a highly cellular (loose/dense) connective tissue.
Loose
The inner (dense/loose) connective tissue layer of the vaginal lamina propria has many thin-walled veins that simulate erectile tissue during sexual arousal.
Dense
Particularly which leukocytes can be found in the vaginal lamina propria?
Neutrophils
Which hormone inhibits further growth of mammary glands in males during puberty?
Testosterone
Which hormone stimulates further development of mammary glands in females during puberty?
Estrogen
Which sensory nerve ending are abundant in the mons pubis and labia majora?
Meissner’s corpuscles
Which female glands are homologous to the male bulbourethral glands?
Bartholin’s glands
What are the glands of the vestibule?
Lesser vestibular glands (Skene’s glands)
Greater vestibular glands (Bartholin’s glands)
The vestibule is lines with what type of cells?
Stratified squamous epithelium
Epithelium present in the female reproductive tract
a. Simple columnar
b. Stratified squamous
c. Stratified columnar
d. Only A, and B
e. A, B and C
e
What is not found in a graafian follicle?
a. Corona radiate
b. Germinal epithelium
c. Theca Interna
d. Granulosa cells
B
The mammary gland is what kind of gland?
Compound tubulo-acinar gland
The zona pellucida is a refractile layer made of…
glycoprotein
What is the fate of the Graafian follicle after ovulation? A. Atresia B. Corpus luteum C. Corpus albicans D. Luteinoma
B
Which structure in the ovary is essential for “estrogen” – defined as baseline serum estrogen level, in normal nonmenopausal women?
Ovarian follicle
Simple columnar in reproductive tract:
a. portio vaginalis
b. endocervix
c. ectocervix
d. vaginal fornix
B
Which of the following appears first in secondary folliculi?
A. Basal lamina
B. Crescent shaped fluid filled cavity
C. zona pellucida
D. Theca folliculi
D
Estradiol is released by:
a. oocyte
b. theca folliculi
c. placental cells
d. granulosa folliculi
D
Most of the ovarian follicle turns into
a. corpus albicans
b. atretic follicles
c. secondary follicles
d. corpus luteum
B
Increased size of mammary glands during pregnancy is a result of
a. development of alveoli in terminal ducts
b. accumulation of adipose tissue
c. increasing amounts of connective tissue
d. milk secretion secreted in alveoli and ducts
A
Male mammary glands are similar to what stage in the female mammary gland development?
a. puberty
b. reproductive
c. lactation
d. menopause
D