Histology Of Stomach Flashcards
GI tract wall has 4 layers:
Mucosa
Submucosa
Muscularis externa
Serosa or adventitia
Epithelium of the stomach : — epithelium
(—- cells- secrete mucous);
–Muscularis externa has an additional —- layer of muscle (allows another dimension of contraction).
Epithelium: Simple columnar epithelium
(goblet cells-mucous);
–Muscularis externa has an additional oblique layer of muscle (allows another dimension of contraction).
Mucosa
• —-, —- surface, —-
• ——- to —— in colour( in pyloric part)
• In contracted state mucosa is folded to form —-.
• rugae are Longitudinal & more marked towards ——- & —— curvature
• Actually rugae are large folds in ——- connective tissue
• Obliterated when stomach is ——/
Mucosa
• Thick, smooth surface, velvety
• Reddish brown to pink in colour
• In contracted state mucosa is folded to form RUGAE.
• They are Longitudinal & more marked towards pyloric & greater curvature
• Actually they are large folds in sub mucosal connective tissue
• Obliterated when stomach is distended
Mucosa has how many layers and list them
3 layers
Epithelium
Lamina propria
Muscularis mucosa
Epithelium
Appears as ——due to small ——- (called—-). Base of gastric pits (foveola) receives gastric glands which
extend deep into ——-
• Epithelium is ——— mucous cells
Epithelium
Appears as honey combed due to small gastric pits (foveola). Base of gastric pits (foveola) receives gastric glands which
extend deep into lamina propria
• Epithelium simple columnar mucous cells
List the gastric glands found in the gastric pits
Cardiac
Principal
Pyloric
State where the 3 gastric glands are located
Principal : body and fundus
Cardiac: near the cardia
Pyloric: numerous mucous and enteroendocrine cells predominate
Principal gastric gland is made up of how many cells and list them
Chief
Parietal
Stem
Mucous
Entero endocrine
What cells predominate in the cardiac glands
Mucous secreting cells
What cells predominate in the cardiac glands
Mucous secreting cells
What cells predominate the pyloric glands
Numerous Mucous and entero endocrine cells
• Gastric glands secrete gastric juices
– Mucous neck cells: in the —— portion
– Parietal cells: found — portion secrete — & ——for vitamin B— absorption
• Gastric glands secrete gastric juices
– Mucous neck cells: in the duct portion
– Parietal cells: mid portion secrete HCl & intrinsic factor for B12 absorption
CHIEF CELLS: found at the —- of gland; secretes —— a precursor molecule to —- (an enzyme that digests protein e that digests protein
CHIEF CELLS: base of gland; secretes pepsinogen a precursor molecule to pepsin (an enzyme that digests protein e that digests protein
Enteroendocrine cells: secrete multiple hormonal products:
——, —-, —-, —-, ——, & ——, which influence several digestive system organs
Enteroendocrine cells: secrete multiple hormonal products:
Gastrin, histamine, endorphins, serotonin, cholecystokinin, & somatostatin, which influence several digestive system organs
• MUCOSAL BARRIER: protects the stomach from its own secretions
– Viscous mucous overlies a thick coating of —-rich mucous
– Tight junctions between epithelial cells are impermeable to —-
– Epithelium is replaced every—to—days
• MUCOSAL BARRIER: protects the stomach from its own secretions
– Viscous mucous overlies a thick coating of HCO - rich
mucous
– Tight junctions between epithelial cells are impermeable to HCl
– Epithelium is replaced every 3-6 days
Lamina Propria
Found in b/w the —-
▪ Contain gastric follicles which are aggregations of ——-
▪ A ————- plexus is also present
Lamina Propria
Found in b/w the glands
▪ Contain gastric follicles which are aggregations of lymphoid tissue
▪ A periglandular vascular plexus is also present
Muscularis mucosa
•Inner —-
•Outer —-
•Ext —- in some places
Muscularis mucosa •Inner circular
•Outer longitudinal
•Ext circular in some places
Sub mucosa
•contain —- type of connective tissue
•Collagen, elastin, —— plexus of stomach is present
Sub mucosa
•Loose connective tissue
•Collagen, elastin, sub mucosal plexus of stomach
Muscularis externa From within outwards layers are
Oblique
Circular
Longitudinal
Oblique fibres
• Limited to ——
• Most developed near the ——
Circular fibres
• Form a —— layer external to oblique fibres
• At the pylorus forms ———
Oblique fibres
• Limited to gastric body
• Most developed near the cardiac orifice
Circular fibres
• Form a uniform layer
external to oblique fibres
• At the pylorus forms annular pyloric sphincter
Longitudinal fibres
• Arranged in 2 groups
• 1st set radiates from ———, best developed along the
curvatures
• 2nd set commence in the —-, passes to —-, some fibres pass to ——, deeper fibres interlace with ——-
Muscle action upper region of stomach forms an area of ——-, lower region has a pump like action, ——- & delivering the contents to duodenum
Longitudinal fibres
• Arranged in 2 groups
• 1st set radiates from cardiac orifice, best developed along the
curvatures
• 2nd set commence in the body, passes to right, some fibres pass to duodenum, deeper fibres interlace with pyloric sphincter
Muscle action upper region of stomach forms an area of storage, lower region has a pump like action mixing & delivering the contents to duodenum
