Histology Of CNS - Olinger 3/21 Flashcards

1
Q

Where are pseudounipolar neurons found?

A

Sensory ganglia of cranial and spinal nerves

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2
Q

What are the types of multipolar neurons?

Located where?

A

Pyramidal and Purkinje

Cerebral cortex (pyramidal)
Cerebellar cortex (Purkinje)
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3
Q

What are the layers of the cerebral cortex from outer to inner?

A
Molecular
External granular
External pyramidal cell
Internal granular
Internal pyramidal cell
Multiform
White matter
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4
Q

Describe cerebellar organization from outer to inner:

A

Molecular layer
Purkinje layer
Granular Layer
white matter

Miles Per Gallon

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5
Q

What is contained in the dendritic shaft?

Dendritic spine?

A

Microtubules

Actin filaments

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6
Q

Function of astrocyte?
Located where?

What special feature does it have?

A

Maintain blood-brain barrier
CNS

End-feet covering neurons, inner PKA, and every blood vessel of CNS

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7
Q

What are the main components of the blood-brain barrier?

What additional components?

A

Tight junctions

Basal lamina of endothelial capillaries
Astrocyte end-feet

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8
Q

In the CNS, the surface of the node is contacted by what?

In PNS, node covered by what?

A

Astrocyte processes

Schwann cell processes

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9
Q

Describe features of oligodendrocytes

A

Provides myelination to several axons in CNS
NO supporting CT
NO basal lamina

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10
Q

What is a microglial cell?

A

Macrophage in the CNS

Like a monocytes

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11
Q

What produces CSF?

A

Choroidal epithelial cells (choroid plexus)

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12
Q

What is characteristic of ependymal epithelium?

Linked by what?

A

Cilia and Microvilli

Desmosomes

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13
Q

Tanocytes are located where?
What do they have?

Linked by what?

A

3rd ventricle
End-feet that extend through the astrocytes to blood vessels

Tight junctions

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14
Q

What is the central canal lined by?

A

Ependymal cells ONLY

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15
Q

What is the choroid plexus?

Located where?

A

Ependyma wrapped around fenestrated blood vessels

Lateral ventricles

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16
Q

What does the arachnoid membrane prevent?

Where does CSF drain to?

A

CSF in subarachnoid space from coming into contact w/fluid of extracellular space of dura mater

Arachnoid villi

17
Q

What is responsible for producing the blood-CSF barrier?

A

Choroidal epithelial cells

18
Q

Where does CSF circulate?

A

Subarachnoid space

19
Q

What is hydrocephalus?

A

CSF unable to leave via arachnoid villus and will accumulate in subarachnoid space

20
Q

What is function of arachnoid villi?

A

Reabsorbed CSF

21
Q

Describe the dura mater

What does it surround?

A

Tough and collage nous

Brain and spinal cord

22
Q

What is pia mater?

A

Single layer of FLAT cells on brain surface

23
Q

Where are bipolar neurons found?

A

Sensory structures

Retina
Olfactory epithelium
Vestibular
Auditory system

ROVA