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Farmacología > Hipolipemiantes > Flashcards

Hipolipemiantes Flashcards

1
Q

Fijadores de ácidos biliares

A

Colestiramina y Colestipol

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2
Q

Colestiramina y Colestipol efecto

A

Less enterohepatic recirculation of bile salts
Increased synthesis of bile salts by the liver
less liver cholesterol
more LDL receptors
Less LDL in blood
HIGHER VLDL and TGs

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3
Q

Inhibidores específicos de absorción

A

Ezetimbina

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4
Q

Ezetimbina efecto

A

menos LDL

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5
Q

HMG-Coa reductase inhibidores

A

Estatinas; Loavastatina

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6
Q

Estatina efecto

A 
less liver cholesterol
more LDL receptores
less plasma LDL
less VLDL y TGs
Mejoran la disfunción endotelial
Disminuyen la respuesta inflamatoria
Disminuyen la respuesta trombógena
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7
Q

Estatina efecto secundario

A

Myopathy
hepatotoxicity
GI - flatulenica

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8
Q

Estatinas con que puede dar con alimento

A

Simvastatina y Rosuvastatina

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Farmacología (25 decks)

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