Antibioticos Flashcards

1
Q

Beta-lactámicos

A

Penicilinas
Cefalosprinas
Monobactámicos
Carbapenemes

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2
Q

Inhibidores de beta-lactamasas

A

Vía parenteral
Ácido claculánico
Sulbactam
Tazobactam

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3
Q

Penicilinas

Espectro más reducido

A

Penicilina G, V
Clzacilina
GP y anaerobias

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4
Q

Penicilinas

Espectro más amplio

A

Amoxixilina
+ Ác claculánico o sulbactam
Pipercailina
GP y GN

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5
Q
Cefalosporinas
1
2
3
4
generacion
A

1 Cefazolina, Cefalexina
2 (Cefoxitina) Cefuroxima, Cefaclor
3 Cefotaxima, (Cefditorem), Ceftriaxone, Cefixima
4 Cefepima

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6
Q

Cefalosporinas 1 generación
Cefalosporinas 2 generación
Cefalosporinas 3 y 4 generación
ATACEN?

A

1 GP
2 GN
3 y 4 GN hospital vía parental

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7
Q

Carbapenemes

Y contra que

A

Imipenem, Meropenem, Ertapenem

GN y GP aerobios y anaeronias

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8
Q

Monobactamicos

Y contra que

A

Aztrenoam

GN

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9
Q

Aminoglucósidos

A

GN aerobicos
Ototoxicidad
Nefrotoxicidad

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10
Q

Inhibitors of bacterial protein synthesis

A

Aminoglycosides 30S
Tetracyclines 30S
Macrolides 50S

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11
Q

Cuales antibióticas se administran en embarazo y lactancia

A

B-lactamicos, Macrolidosm fosfomicina

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12
Q

Hepatotoxicidad

A

Sulfamidas, Aminoglucosidos

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13
Q

Anemia

A

Sulfamidas, cloranfenicol

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14
Q

No metabolismo hepatico

A

Penicilina

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15
Q

Actividad bactericida es dosis depeniente

A

Impinem

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16
Q

Reaccion no cruzada con P y C

A

Aztreonan

17
Q

Resistencia a b lactamasas

A

Impinem

Aztreonan

18
Q

Tunberculosis

A

Estroptomicina

19
Q

Topica

A

Neomicina

20
Q

Aminoglucosido sintetico

A

Amikacina

21
Q

Efecto postantibiotico bacteriostatico

A

Aminoglycosides

22
Q

Inhibitors of bacterial protein synthesis

A

Aminoglycosides (bacteriocidal), Cloramphenicol, Macrolides, Tetracyclines

23
Q

Inhibition of nucleic synthesis

A

Fluoroquinone, Rifampin

24
Q

Inhibition of folic acid synthesis

A

Sulfonamides, Trimetophrim, Pyrimethamine

25
Q

Aminoglycosides efectos secundarios

A

Nefrotoxicity

Ototoxicity

26
Q

Tetraciclinas actuan contra

A
GP y GN 
Ricketsia
Brucella
Cólera
Micoplasma
Chlamydia
\+ Déposito en dientes
27
Q

2 uso después de penicilinas

A

Macrolidos -> Eritromicina, Claritromizina, Azitromicina (cardiopatía)

28
Q

Resistencias cruzadas son poco frecuentes con

A

Macrolidos

29
Q

Sulfamidas inhiben

A

Dihidropteroico sintetasa

- PABA + Pteridina

30
Q

Sulfamidas se usan en combinacion con:

A

Trimetophrim + sulfamethoxazole COTRIMOXAZOL

Pyrimethamine + sulfadiazine

31
Q

Trimethoprim inhiben

A

Dihidrofolato reductasa

No tenemos Ac tetrahidrofólico

32
Q

Quinolones inhibit

A

DNA gyrase

33
Q

Quinolones usos

A

Infeciones urinarias intestinales y biliares

GN