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Wilkins > Hepatits > Flashcards

Hepatits Flashcards

0
Q

HBV

A

Serum

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1
Q

IgM anti-HAV

A

Recent HAV infection

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2
Q

Dane particle

A

Another name for HBV

Etiologic agent for hepatitis B

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3
Q

HbsAg

A

Surface marker in acute disease and carrier state

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4
Q

anti-HBs

A

Indicates:
Active immunity to HBV (past infection)
Passive immunity from HBIG
Immune response from HB vaccine

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5
Q

HbeAg

A

Hepatitis B e antigen

High infectivity

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7
Q

anti-Hbe

A

Low titer HBV (low degree infectivity)

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8
Q

anti-HBc

A

antibody to hepatitis B core antigen

indicates prior HBV infection

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9
Q

IgM anti-HBc

A 
IgM class antibody to hepatitis B
indicates recent HBc infection
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10
Q

HBV-DNA

A

DNA of HBV

detected by nucleic acid amplification

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11
Q

HAV transmission

A

fecal-oral route
waterborne and food-borne
blood

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12
Q

HAV fecal-oral route of transmission

A

most common transmission

through close contact in unsanitary conditions

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13
Q

HAV waterborne and food-borne transmission

A

epidemics may occur when sanitation is inadequate.
contaminated water
infected food handlers

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14
Q

HAV blood transmission

A

earliest days of active disease the blood contains transient hepatitis A viruses
transmission by blood transfusion is rare

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15
Q

HAV incubation

A

15-50 (or 45?) with an average of 30 days

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16
Q

HBV transmission

A

blood and other body fluids

perinatal transmission

17
Q

HBV transmission: blood and other body fluids

A

nearly all body fluids carry virus, but only blood, saliva, semen, and vaginal fluids have been shown to be infectious

18
Q

HBV viruses have been found in

A 
gingival sulcus fluid
menstrual blood
tears
urine
perspiration
nasopharyngeal secretions
19
Q

HBV transmission by percutaneous and permucosal exposure

A

percutaneous (intravenous, intramuscular, subcutaneous)
accidents w/ needle stick or other sharp instruments
perinatal exposure
contaminated needles
sexual exposure
infection from blood transfusion & blood products (rare b/c all donors are screened)

20
Q

HBV transmission by perinatal transmission

A

pregnancy: transmission of virus to fetus can occur & newborn exposed during birth
infant infected @ high risk for chronic infection liver disease or liver cancer

21
Q

HBV incubation

A

45-180 days

22
Q

HCV incubation

A

14-180 days or 1-6 months

23
Q

HCV transmission

A

percutaneous exposure (contaminated needles or syringes, plasma derivatives, transfusion, accidental needle stick)
has been demonstrated in saliva
nonpercutaneous route include sexual transmission and perinatal exposure

24
Q

HDV transmission

A

direct exposure to contaminated blood and serous body fluids
contaminated needle and syringes
sexual contacts
perinatal transfers

25
Q

HEV incubation

A

15-60 days

26
Q

HEV transmission

A

contaminated water

person-to-person by fecal-oral route

Wilkins (23 decks)

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