AIDS Flashcards
Study guide for AIDS quiz on 9/16
HIV is a disease that occurs because of a defect in
cell mediated immunity
HIV is a
retrovirus
_________ is the core genetic material
RNA
______________ is essential for replication
reverse transcriptase
the two phases of the complex life cycle of the HIV-1 are
establishment of infection and production of new virus particles
HIV enters the body and passes by way of the blood to a target cell, where it binds to specific cellular receptor,
CD4+
Target cells that have CD4+ receptors include: _________, macrophages, monocytes, and certain neurons and glial cells of the brain
T-helper lymphocytes
only the viral RNA and the ____________ enter the cell
enzymes
single stranded DNA is then translated to double stranded, it is called a
provirus
blood count of 500 is considered what category?
Category 1
What blood count is critical?
less than 200
what clinical category does candidiasis, oropharyngeal (thrush) fall under
category B
Brukitt’s lymphoma is associated with__and falls under what category?
EVB, Category C
what clinical category does Kaposi’s sarcoma fall under
Category C
laboratory count is
CD4+ cells
what is considereed a predictor for Pneumocytis carinii pneumonia?
candidiasis
three periodontal disease lesions that are strongly associated with HIV
- linear gingival erythema (LGE)
- necrotizing ulcerative gingivitis (NUG)
- necrotizing ulcerative periodontitis (NUP)
give a description of LGE
a 2-3 mm red band may appear along the gingival margin with petechia-like and/or diffuse red lesions of the attached gingiva
give a description of NUG
ulcerization and destruction of interdental papillae with spontaneous bleeding and pain my develop rapidly
give a description of NUP
rapid destruction and loss of periodontal attachment and severe soft tissue destruction that occurs in less than 6 month time period
which of the herpes viruses can establish a latent infection in the trigeminal nerve ganglion that can reactivate and erupt in a surface lesion later?
Herpes Simplex Virus I
AIDS is associated with infection by the _______ virus
HIV
a count of what serologic marker is most often used to evaluate and monitor the progression of HIV infection?
EIA or ELISA most common used tests and are sensitive and specific
as the count of indicator cells decreases, the symptoms of disease and the incidence of oral infections or oral lesions related to the HIV infection
increase
what are the most common oral lesions associated with HIV infection?
- candidiasis
- erythematous
- psuedomembranous
- hairy leukoplakia
- kaposi’s sarcoma
- non hodgkin’s lymphoma
- periodontal infection
what oral lesion associated with HIV is a fungal infection?
candidiasis
what oral lesion associated with HIV is a viral infection?
hairy leukoplakia
what oral lesion associated with HIV is a bacterial infection?
periodontal infection
