Hepatitis Virus Diagnosis and Therapy Flashcards
HAV diagnosis?
Anti-HAV IgM (IgG shows prior infection)
HBV diagnosis?
Multiple serological markers
HCV diagnosis?
Anti-HCV antibody, RT-PCR
HDV diagnosis?
Anti-HDV delta-antigen IgM
HEV diagnosis?
Anti-HEV IgM, IgG
Rule out HAV infection
Therapy for HAV?
Supportive, pooled IgG
Therapy for HBV?
a-interferon, lamivudine, HepB IgG
Therapy for HCV?
a-interferon, ribavirin, boceprevir, telaprevir
Therapy for HDV?
a-interferon, lamividine, HepB IgG
Treat same as HBV
Therapy for HEV?
None
Which hepatitis viruses have vaccines?
HAV, HBV
Why do you not vaccinate against HDV?
Needs HBV so HBV vaccination is effective
Why can’t you vaccinate against HCV?
Antigen differentiation over the course of an infection