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Ned's PassMed notes 2019/20 > Hepatitis > Flashcards

Hepatitis Flashcards

1
Q

describe the typical LFT findings in hepatitis

A

HIGH transaminases - AST/ALT

LESS of a rise in ALP

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2
Q

what are transaminases

A

liver enzymes that are released into the blood as a result of inflammation of liver cells

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3
Q

what is the most common viral hepatitis worldwide

A

Hep A

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4
Q

is Hep A RNA or DNA virus

A

RNA

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5
Q

how is HepA transmitted

A

faecal-oral route

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6
Q

how is hep A managed

A

resolves itself in 1-3 months

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7
Q

is there a vaccine for hep A

A

yes

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8
Q

how is Hep B spread

A

blood or bodily fluids

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9
Q

can hep B be transmitted from mother to child during pregnancy

A

yes - vertical transmission

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10
Q

is hep B RNA or DNA virus

A

DNA

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11
Q

how is Hep B treated

A

90% of patients will recover in 2 months

10% will become chronic hep B carriers

Vaccination

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12
Q

what does a surface antigen indicate (HBsAg) in hepB

A

active infection

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13
Q

what is a marker of high infectivity in hep B

A

E antigen (HBeAg)

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14
Q

what antigen implies past or current infection in hepB

A

core antibodies (HBcAb)

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15
Q

what is a direct count of the virus load in hep B

A

hep B virus DNA (HBV DNA)

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16
Q

what does the surface antibody in hep B indicate

A

vaccination or past or current infection

17
Q

in what percentage of patients does Hep C become chronic

A

75%

18
Q

what are 2 complications of hepC

A

liver cirrhosis

hepatocellular carcinoma

19
Q

is hep C DNA or RNA

A

RNA

20
Q

is there a vaccine for hep C

A

NO - there is an antiviral mediation which cures it now tho

21
Q

what is the screening test for hep C

A

hep C antibody

22
Q

what is used to confirm diagnosis of hep C

A

hep C RNA testing

23
Q

which hep virus can only survive alongside hepB

A

hep D

24
Q

what effect does hep D have

A

increases the severity of hep B infection

25
Q

is hep D DNA or RNA

A

RNA

Ned's PassMed notes 2019/20 (17 decks)

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