Hemostasis and Coagulation

Question 1

define Hemostasis

Answer 1

It is the physiological process wherein bleeding is prevented at the site of injury while maintaining a normal blood flow at other places of circulation.

Question 2

Major steps of hemostasis

Answer 2

1. Vasoconstriction
2. Platelet plug for temporary blockage
3. Formation of fibrin clot

Question 3

The action or process of a liquid, especially blood, changing to a solid or semi-solid state.
Initiated by what cells>

Answer 3

Coagulation
- blood platelets

Question 4

Principal factors in homestasis

Answer 4

1. Vascular/ Endothelium
2. Thrombocyte / Platelets
3. Clotting mechanism

Question 5

Antithrombotic properties of endothelial cells

Answer 5

1. Prostacyclin release
2. nitric oxide
3. Heparan sulfate expression
   …many more

Question 6

Platelets are cytoplasmic fragments from what cells?

Answer 6

Megakaryocyte