Hemostasis

Question 1

What are the 3 main aspects of hemostasis?

Answer 1

1. Primary hemostasis; activated platelets form a plug
2. Secondary hemostasis; reinforcement of the plug with fibrin strands (within hours)
3. Fibrinolysis; dissolution of clot after vascular wall repairs (over days)

Question 2

All coagulation factors are made in the liver except for which one?

Answer 2

Factor VIII (8)

Question 3

Vitamin K is required for formation of which coagulation factors?

Answer 3

II (2)
VII (7)
IX (9)
X (10)

Question 4

The initiation of the coagulation cascade is primarily through exposure of what?

Answer 4

Tissue factor AKA factor III (3)