hemolytic anemia Flashcards
1
Q
what is hemolytic anemia
A
episodic or continuous premature RBC destruction associated with: active hyper cellular bone marrow high reticulocytes in blood high blood lactic dehydrogenase low blood haptoglobin increased bilirubin in blood
2
Q
hemolytic anemia intrinsic hereditary
A
spherocytosis
g6pd deficiency
hemoglobinopathies
3
Q
hemolytic anemia extrinsic hereditary
A
autoimmune, mechanical, malaria
infection by parvovirus b19 can lead to transient aplastic crisis–> important in kids
4
Q
clinical manifestation of hemolytic anemia
A
symptoms of anemia jaundice- under tongue pallor gall stones infection can lead a hemolytic crisis
5
Q
labs for hemolytic anemia
A
CBC-Hgb low or falling CMP- LDH-high indirect bilirubin: high retic: high ua: heoglobinuria direct Coombs test looking for antibodies on the RBC
6
Q
hemolytic anemia treatment
A
typically includes corticosteroids and iron supplementation
