Hemoglobin Forms Flashcards
1
Q
HbA
A
a2B2
Normal adult form
2
Q
HbGower
A
Z2E2 (zeta/episolon)
Earliest in fetus
synthesized by yolk sac
3
Q
HbBart
A
y4
homozygous alpha thalassemia
Increased affinity for O2 but doesn’t release it
hydrops fetalis and death in utero
4
Q
HbA2
A
a2D2 (alpha/delta)
normal variant represents 2-5% of hemoglobin
5
Q
HbF
A
a2 y2 (alpha/gamma) Fetal to 6 months of life
