Hematopoiesis

Question 1

It is the major hematopoietic organ.

Answer 1

bone marrow

Question 2

present in first few hours after ovum fertilization and most versatile

Answer 2

totipotential

Question 3

embryo development into fetus

Answer 3

totipotential

Question 4

several days after fertilization

Answer 4

pluripotential

Question 5

cannot develop into a fetus but can develop into any cell type

Answer 5

pluripotential

Question 6

derived from pluripotent stem cells and lmited to specific cell types

Answer 6

multipotent

Question 7

start in hematopoiesis in the embryonic yolk sac
(declines by the 3rd month)

Answer 7

19th day

Question 8

number of month/s that liver is involved in hematopoiesis

Answer 8

1st month

Question 9

It is the month where ossification and bone marrow involvement starts.

Answer 9

4th month

Question 10

The month when the liver takes over hematopoiesis

Answer 10

5th month

Question 11

The month when bone marrow assumes its ultimate role as primary site of hematopoiesis.

Answer 11

After 5 months

Question 12

Name the phase:

19th day after fertilization

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 12

Mesoblastic phase

Question 13

Name the phase:

site: embryonic yolk sac

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 13

Mesoblastic phase

Question 14

Name the phase:

1st Trimester (5-7 weeks)

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 14

Hepatic phase

Question 15

Name the phase:

liver involvement

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 15

Hepatic phase

Question 16

Name the phase:

2nd trimester (4th - 6th months)

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 16

Hepatic phase

Question 17

Name the phase:

Fifth month where HSC and mesenchymal cells migrate to core bones

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 17

Medullary/Myeloid phase

Question 18

Name the phase:

6th month: BM is the primary site of production

(Mesoblastic, Hepatic, Medullary/Myeloid)

Answer 18

Medullary/Myeloid phase

Question 19

Identify the globin chains

Hb A (adult)

Answer 19

alpha + beta

Question 20

Identify the globin chains

Hb A2

Answer 20

alpha + delta

Question 21

Identify the globin chains

Hb F

Answer 21

alpha + gamma

Question 22

Hematopoietic Progenitor Cells (HPCs) have _____ where erythropoisis and enucleation occurs.

Answer 22

Erythropoietic Islands

Question 23

It is a phagocytic cell which forms the lining of the sinusoids of the liver.

Answer 23

Kupffer cells