Hematopoiesis Flashcards
It is the major hematopoietic organ.
bone marrow
present in first few hours after ovum fertilization and most versatile
totipotential
embryo development into fetus
totipotential
several days after fertilization
pluripotential
cannot develop into a fetus but can develop into any cell type
pluripotential
derived from pluripotent stem cells and lmited to specific cell types
multipotent
start in hematopoiesis in the embryonic yolk sac
(declines by the 3rd month)
19th day
number of month/s that liver is involved in hematopoiesis
1st month
It is the month where ossification and bone marrow involvement starts.
4th month
The month when the liver takes over hematopoiesis
5th month
The month when bone marrow assumes its ultimate role as primary site of hematopoiesis.
After 5 months
Name the phase:
19th day after fertilization
(Mesoblastic, Hepatic, Medullary/Myeloid)
Mesoblastic phase
Name the phase:
site: embryonic yolk sac
(Mesoblastic, Hepatic, Medullary/Myeloid)
Mesoblastic phase
Name the phase:
1st Trimester (5-7 weeks)
(Mesoblastic, Hepatic, Medullary/Myeloid)
Hepatic phase
Name the phase:
liver involvement
(Mesoblastic, Hepatic, Medullary/Myeloid)
Hepatic phase
Name the phase:
2nd trimester (4th - 6th months)
(Mesoblastic, Hepatic, Medullary/Myeloid)
Hepatic phase
Name the phase:
Fifth month where HSC and mesenchymal cells migrate to core bones
(Mesoblastic, Hepatic, Medullary/Myeloid)
Medullary/Myeloid phase
Name the phase:
6th month: BM is the primary site of production
(Mesoblastic, Hepatic, Medullary/Myeloid)
Medullary/Myeloid phase
Identify the globin chains
Hb A (adult)
alpha + beta
Identify the globin chains
Hb A2
alpha + delta
Identify the globin chains
Hb F
alpha + gamma
Hematopoietic Progenitor Cells (HPCs) have _____ where erythropoisis and enucleation occurs.
Erythropoietic Islands
It is a phagocytic cell which forms the lining of the sinusoids of the liver.
Kupffer cells
