ALL

Question 1

small and homogenous

Answer 1

FAB L1

Question 2

most common in children

Answer 2

FAB L1

Question 3

T cells ALL are

Answer 3

FAB L1

Question 4

large and heterogenous

Answer 4

FAB L2

Question 5

adult ALL

Answer 5

FAB L2

Question 6

large but homogenous

Answer 6

FAB L3

Question 7

lymphoblast are vacuolated

Answer 7

FAB L3

Question 8

t(8;14)

Answer 8

FAB L3

Question 9

neoplasm of lymphoblasts committed to the B-cell lineage

Answer 9

precursor B-call ALL

Question 10

more common in CLL but there is a small percent that cab present in ALL

Answer 10

t(9;22)

Question 11

t4;11)

Answer 11

B-cell ALL

Question 12

neoplasm of lymphoblasts committed to the T-cell lineage

Answer 12

precursor T-cell ALL

Question 13

remnants of cells that lack any identifiable cytoplasmic membrane or nuclear structure

Answer 13

Smudge cells/basket cell

Question 14

TdT

Answer 14

Terminal deoxynucleotidyl transferase

Question 15

intracellular enzyme that catalyzes that nonspecific incorporation of nucleotides into DNA

Answer 15

TdT

Question 16

cALLA

Answer 16

common ALL antigen

Question 17

expression is associated with inferior survival in adults ALL

Answer 17

CD 20

Question 18

only marker expressed through all stages of B cells

Answer 18

CD19

Question 19

BCR is on chromosome?

Answer 19

22

Question 20

ABL is on chromosome?

Answer 20

9

Question 21

marker for primary granules and Auer rods

Answer 21

MPO stain

Question 22

stains peroxidase present in the granulocytes

Answer 22

MPO Stain

Question 23

(+) acute myeloid & monocytic leukemia

(-) ALL

Answer 23

MPO stain

Question 24

(+) acute myeloid/myelomonocytic leukemia

(-)ALL

Answer 24

Sudan Black B stain

Question 25

markers for phospholipids and lipids

Answer 25

SBB stain

Question 26

marker for glycogen glycoproteins

Answer 26

Periodic Acid Shiff stain

Question 27

marker for mucoproteins and high molecular weight carbohydrates

Answer 27

Periodic Acid Shiff stain

Question 28

(+) ALL
(+) erythroblasts
(-) AML

Answer 28

Periodic Acid Shiff stain

Question 29

(+) FAB M6 erythroleukemia/Di Guglielmo syndrome

Answer 29

PAS stain

Question 30

known as specific esterase

Answer 30

Naphthol As-D Chloroacetate Esterase (NASDCA)

Question 31

stains esterase present in granulocytes

Answer 31

NASDCA

Question 32

(+) granulocytic cells

(-) monocytic cells

Answer 32

NASDCA

Question 33

stable enzyme that lasts for months

Answer 33

NASDCA

Question 34

known as nonspecific esterase

Answer 34

alpha-naphthyl acetate-butyrate esterase

Question 35

inhibition by NaF

Answer 35

alpha-naphthyl acetate-butyrate esterase

Question 36

marker for monocytes, promonocytes, and monoblasts and megakaryocytes

Answer 36

alpha-naphthyl acetate-butyrate esterase

Question 37

(+) monocytic cells

(-) granulocytic cells

Answer 37

alpha-naphthyl acetate-butyrate esterase

Question 38

stain used for T-lymphocytes

Answer 38

ACP stain

Question 39

present in all hematopoietic cells and found in lysosomes

Answer 39

ACP stain

Question 40

uses L-tartaric acid

Answer 40

ACP

Question 41

cytoplasm is light blue, vacuolated, and has hairy projections

Answer 41

Hairy cell leukemia

Question 42

TRAP (+) Tartrate-Resistant Acid Phosphatase

Answer 42

Hairy cell leukemia

Question 43

used to differentiate CML from neutrophilic leukemoid reaction

Answer 43

Neutrophil Alkaline Phosphatase

Question 44

LAP score (Kaplow count: 100 neutrophils)

Answer 44

NAP

Question 45

decreased LAP < 10:

increased LAP > 10:

Answer 45

decreased LAP < 10: CML, PNH

increased LAP > 10: NLR, pregnancy,PV, myelofibrosis