Hematologic System Flashcards

Question

Filgrastim/Pegfilgrastim Administration

Answer 1

``` subcutaneous injection (filgrastim), IV (pegfilgrastim) do not agitate vial monitor CBC ```

Answer 2

stimulate platelet production | thrombocytopenia related to cancer

Answer 3

fluid retention blurred vision cardiac dysrhythmia

Answer 4

administer within 6-24 hours after chemotherapy | subcutaneous injection

Answer 5

dilute liquid preparations with juice or water and administer with plastic straw/syringe encourage orange juice fortified with vitamin C (vitamin C facilitates absorption) avoid antacids, coffee, tea, dairy products, whole grain breads concurrently or for 1 hr after administration monitor for constipation and GI upset for IM injection use Z-track, do not massage injection site, never use deltoid for IV administration use test dose first

Answer 6

``` Heparin Low molecular weight heparin (enoxaparin) warfarin dabigatran rivaroxaban ```

Answer 7

``` stroke pulmonary embolism deep vein thrombosis cardiac catheterization MI DIC ```

Answer 8

venous thrombosis prevent thrombus formation for clients who have atrial fibrillation or prosthetic heart valves prevent recurrent MI prevent transient ischemic attacks

Answer 9

administer subcutaneously or IV incompatible with many medications avoid NSAIDs, aspirin, medications containing salicylates

Answer 10

Pregnancy Category X contraindicated in thrombocytopenia, vitamin K deficiency, liver disease, alcohol use disorder decreased effects with phenobarbital, carbamazepine, phenytoin, oral contraceptives food high in vitamin K may decrease effects

Answer 11

hemorrhage heparin induced thrombocytopenia toxicity/overdose

Answer 12

hemorrhage | toxicity/overdose

Answer 13

Heparin: monitor aPTT every 4-6 hours for IV administration monitor for signs of bleeding, implement bleeding precautions administer subcutaneous to abdomen, 2 inches from umbilicus, do not massage or aspirate rotate injection sites and observe for bleeding or hematoma administer protamine sulfate for toxicity

Answer 14

administer once daily monitor INR or PT avoid NSAIDs and medications with aspirin wear medical alert bracelet, bleeding precautions administer vitamin K for toxicity ginger, garlic, gingko, ginseng may increase risk of bleeding avoid alcohol

Answer 15

``` Aspirin Abciximab Clopidogrel Ticlopidine Pentoxifylline Dipyridamole ```

Answer 16

prevention of acute MI or acute coronary syndrome prevent stroke intermittent claudication

Answer 17

contraindicated in thrombocytopenia | use caution in peptic ulcer disease

Answer 18

prolonged bleeding gastric bleeding thrombocytopendia

Answer 19

monitor for signs of prolonged bleeding | report tarry stool, ecchymosis

Answer 20

Alteplase Tenecteplase Reteplase

Answer 21

Acute myocardial infarction deep vein thrombosis massive pulmonary emboli ischemic stroke

Answer 22

contraindicated in intracranial hemorrhage, active internal bleeding, aortic dissection, brain tumors use caution with severe hypertension concurrent use of anticoagulants or antiplatelet medications increases risk for bleeding

Answer 23

serious bleeding risks from recent wounds, puncture sites, weakened vessels hypotension possible anaphylactic reaction

Answer 24

administration must take place within 4-6 hrs of onset continuous monitoring is acquired clients will begin anticoagulant therapy to prevent repeat thrombotic event