Cardiovascular System Flashcards

1
Q

ACE Inhibitor Examples

A
Captopril
Enalapril
Enalaprilat
Fosinopril
Lisinopril
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2
Q

ARBS Inhibitors Examples

A

Losartan
Valsartan
Irbesartan

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3
Q

ACE Inhibitors Indications

A

Hypertension
Heart Failure
MI
Diabetic Nephropathy

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4
Q

ARBS Inhibitors Indications

A

Hypertension
Heart Failure
MI
Diabetic Nephropathy

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5
Q

ACE Inhibitors Precautions

A

Use caution with diuretic therapy
Monitor potassium levels
pregnancy

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6
Q

ARBS Inhibitors Precautions

A

Use caution with diuretic therapy
Monitor potassium levels
pregnancy

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7
Q

ACE Inhibitors Complications

A

persistent nonproductive cough
angioedema
hypotension

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8
Q

ARBS Inhibitors Complications

A

hypotension

angioedema

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9
Q

ACE inhibitor Administration

A

take 1 hour before meals
monitor blood pressure
monitor for angioedema, give epinephrine if develops

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10
Q

ARBS Inhibitor Administration

A

monitor blood pressure

monitor for angioedema, give epinephrine if develops

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11
Q

Calcium Channel Blockers Examples

A

Nifedipine
Verapamil
Diltiazem
Amlodipine

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12
Q

Calcium Channel Blockers Indications

A

angina
hypertension
a-fib, a-flutter, SVT

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13
Q

Calcium Channel Blockers Precautions

A

use caution with digoxin and beta blockers
contraindicated in heart failure, heart block, bradycardia
do not consume grapefruit juice

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14
Q

Calcium Channel Blockers Complications

A

Constipation
Reflex tachycardia
Peripheral edema
toxicity

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15
Q

Calcium Channel Blockers Administration

A

slowly taper dose when discontinuing
monitor heart rate and blood pressure
administer IV injection over 2-3 min

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16
Q

Alpha 1 Adrenergic Blockers Examples

A

Prazosin

Doxazosin mesylate

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17
Q

Alpha 1 Adrenergic Blockers Indications

A

Primary hypertension

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18
Q

Alpha 1 Adrenergic Blockers Precautions

A

Increased risk of hypotension and syncope if given with other antihypertensives, beta blockers, diuretics
NSAIDs may decrease effects prazosin

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19
Q

Alpha 1 Adrenergic Blockers Complications

A

Dizziness

Fainting

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20
Q

Alpha 1 Adrenergic Blockers Administration

A

monitor heart rate and blood pressure
take medications at bedtime to minimize effects of hypotension
consult doctor before taking OTC medications

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21
Q

Central Alpha 2 Adrenergic Agonists Examples

A

Clonidine
Guanfacine
Methyldopa

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22
Q

Central Alpha 2 Adrenergic Agonists Indications

A

Primary hypertension
Hypertensive crisis
Severe cancer pain

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23
Q

Central Alpha 2 Adrenergic Agonists Precautions

A

Contraindicated with anticoagulation therapy, MAOIs
Contraindicated with liver failure, breastfeeding
Use caution with CVA, MI, diabetes mellitus, major depression, chronic renal failure

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24
Q

Central Alpha 2 Adrenergic Agonists Complications

A
dry mouth
drowsiness and sedation
rebound hypertension
black or sore tongue
leukopenia
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25
Central Alpha 2 Adrenergic Agonists Administration
monitor for adverse CNS effects monitor CBC, heart rate, blood pressure assess for weight gain and edema monitor closely for rebound hypertension 48hrs after discontinuing medication take at bedtime to minimize effects of hypotension notify provider of involuntary jerky movements, prolonged dizziness, rash, jaundice
26
Beta Adrenergic Blockers Examples
``` Metoprolol Atenolol Propranolol Nadolol Labetalol ```
27
Beta Adrenergic Blockers Indications
``` Primary hypertension angina tachydysrhythmias heart failure MI ```
28
Beta Adrenergic Blockers Precautions
Contraindicated in AV block, sinus bradycardia, asthma, bronchospasm, heart failure may mask effects of hypoglycemia in patients with diabetes mellitus
29
Beta Adrenergic Blockers Complications
bradycardia nasal stuffiness AV block bronchospasm
30
Beta Adrenergic Blockers Administration
do not stop abruptly as may induce rebound myocardium excitation hold medication if systolic blood pressure less than 100 mmHg or pulse less than 60 bpm monitor diabetic clients for indication of hypoglycemia
31
Vasodilators Examples
Nitroglycerin Enalaprilat Nitroprusside Hydralazine
32
Vasodilators Indications
Hypertensive emergencies
33
Vasodilators Precautions
hepatic or renal disease elderly electrolyte imbalances
34
Vasodilators Complications
Dizziness Headache Profound hypotension Cyanide toxicity/thiocyanate poisoning
35
Vasodilators Administration
continuous EKG and blood pressure monitoring keep medication covered discard unused medication after 24 hrs
36
Digoxin Indications
Heart failure | Atrial fibrillation
37
Digoxin Precautions
Thiazide of loop diuretics increase risk of hypokalemia and precipitate digoxin toxicity ACE and ARBs increase risk of hyperkalemia Verapamil increases risk of toxicity
38
Digoxin Toxicity
anorexia, nausea/vomiting, abdominal pain fatigue/weakness diplopia, blurred vision, halos around object
39
Digoxin Administration
Assess apical pulse for 1 minute prior to administration, do not give if less than 60 bpm (70 bpm for child, 90 bpm for infant) monitor for signs of digoxin toxicity, hypokalemia, hypomagnesemia maintain therapeutic digoxin level: 0.6-1.2
40
Digoxin Toxicity Treatment
discontinue digoxin and potassium wasting medication treat dysrhythmias with phenytoin or lidocaine treat bradycardia with atropine Digoxin immune FAB if overdose
41
Nitrates Indications
Acute angina attack | prophylaxis of chronic stable or variant angina
42
Nitrates Precautions
contraindicated in clients with head injury hypotensive risk with antihypertensive medications contraindicated if taking erectile dysfunction medications
43
Nitrates Complications
headache orthostatic hypotension reflex tachycardia tolerance
44
Nitrates Administration
administer sublingual rest 5 minutes, if pain not relieved call 911 and administer second tablet, may take up to 3 tablets keep in dark container may be taken prophylactically before exercise wear gloves before administering topical ointment rotate skin sites, usually worn 12-14 hours and then removed
45
Adenosine Class
Antidysrhythmic
46
Adenosine Indications
convert SVT to sinus rhythm
47
Adenosine Complications
flushing nausea bronchospasm prolonged asystole
48
Adenosine Administration
Rapid IV push over 1-2 sec | flush immediately with normal saline
49
Amiodarone Class
Antidysrhythmics
50
Amiodarone Indications
Ventricular fibrillation | Unstable ventricular tachycardia
51
Amiodarone Complications
Bradycardia cardiogenic shock pulmondary disorders
52
Amiodarone Administration
incompatible with heparin may be given in PO maintenance dose monitor for respiratory complications
53
Atropine Class
Antidysrhythmics
54
Atropine Indications
bradycardia known exposure to chemical nerve agents reduce secretions
55
Atropine Complications
``` dry mouth blurred vision photophobia urinary retention constipation ```
56
Atropine Administration
when used for life threatening emergency, has no contraindications
57
Statin Examples
``` Atorvastatin Simvastatin Lovastatin Pravastatin Rosuvastatin Fluvastatin ```
58
Statin Indications
hypercholesterolemia | prevention of coronary events
59
Statin Complications
muscle aches hepatotoxicity rhabdomyolysis peripheral neuropathy
60
Statin Precautions
prolonged bleeding in clients taking warfarin drug interactions with: digoxin, warfarin, thyroid hormones, thiazide diuretics, phenobarbital, NSAIDs, tetracycline, beta blockers, gemfibrozil, glipizide, glyburide, oral contraceptives, phenytoin do not administer with grapefruit juice
61
Cholesterol Absorption Inhibitor Example
Ezetimibe
62
Cholesterol Absorption Inhibitor Administration
take 2 hours before or 4 hours after other antilipemics | risk of liver damage increased when combined with statins
63
Statins Administration
take medication in the evening when cholesterol synthesis increases monitor liver and renal function labs low-fat/high fiber diet