Heart Failure Flashcards
What is heart failure?
Inability of the heart to meet the demands of the body
What can cause heart failure?
IHD
Hypertension
Aortic stenosis
Arrhythmias
How does IHD cause heart failure?
Myocardial dysfunction due to scarring and remodelling
How does hypertension cause heart failure?
Increased afterload on ventricles
Accelerates atherscelerosis
How does aortic stenosis cause heart failure?
Increased afterload on ventricles
What can influence stroke volume?
Pre-load
Myocardial contractility
After-load
What is pre-load
The stretch on the ventricle just before contraction
- volume in ventricle at end of diastole
What is after-load?
Force heart has to contract against
- total peripheral resistance
What is Frank-Starling’s law?
More ventricular distension during diastole = greater volume ejected during systole
Why is CO reduced in heart failure?
Reduced pre-load
- impaired filling
Reduced myocardial contractility
- heart muscle no longer able to produce same force of contraction
Increased after-load
- increased pressure ventricle contracting against
- aortic stenosis or hypertension
What are the 2 main reasons a heart can fail?
Filling problem
- diastolic
Ejection problem
- systolic
How is heart failure classified?
Heart failure with reduced ejection fraction
- systolic dysfunction
Heart failure with preserved ejection fraction
- diastolic dysfunction
How is ejection fraction calculated?
Amount of blood pumped out of ventricle / total amount of blood in ventricle
What is normal ejection fraction?
> /= 50%
What is reduced ejection fraction?
<40%