Head Trauma II Flashcards
_____ does not need to be lost or impaired to diagnose a mild TBI
Consciousness
These three areas make up the tests for the Glascow Coma Scale
Eye, motor, and verbal response
A GCS score of more than 12 indicates a _____ TBI
mild
There is a ______ age demographic for people at risk for mild TBI
trimodal- kids, young adults, and the elderly
Physical symptoms of mTBI include headache, nausea, and _____ to light and sound
sensitivity
Cognitive symptoms of mTBI typically revolve around loss of ______
memory
Patients can feel more ______ after a mTBI (symptom)
emotional
______ symptoms of mTBI have a wide variance (too much, too little of this)
sleep
____ loading is a direct impact to the head
contact
_____ loading is when the brain bounces around inside the skull after rapid motion
Inertia
All injuries do include an ______ component
inertial
The human brain is uniquely vulnerable to ____ acceleration
rotational
_____ matter is particularly vulnerable to shear stress and is the major factor in mild TBI pathology
White
Rapid motion causes damage to axons due to their ______ property (think of silly putty)
viscoelastic
_____ (structure) in the axons, not the axons themselves, typically break during mTBI
Microtubules
_____ (location) structures are the most vulnerable to DAI
Midline
_____ _____ ____ is the molecular marker of DAI
Amyloid Precursor Protein
Primary ______ is the most important cause of pathology in mild TBI- that is, ______ injury (type) is typically not present
DAI; secondary
____ (molecular marker) has been found in the blood of patients with mild TBI, as it is an axonal protein
SNTF
Impact in the _____ plane is highly correlated with loss of consciousness
axial
_____ ___ imaging can show the integrity of the white matter tracts
Diffusion Tensor
Post concussive disorder may be due to __-_____ _____, not the mTBI itself
pre-existing conditions
CTE tends to localize to the _____ and ____ lobes
temporal and frontal
There is marked _____ (descriptor) ____ atrophy
global cerebral
_____ _____ ____ is the near or complete loss of the septum pellucidum
Cavum septum pellucidum
Beware of _____ ____ when looking at CTE data due to limited sample size and high profile cases
selection bias
What are the pathological diagnostic criteria for CTE?
There are none, gotcha
