HC 4 Flashcards
Medically unexplained physical symptoms (MU(P)S)
No medical cause or no identifiable physical distortions or disruptions of bodily processes
- often disappear spontaneously
- sometimes persist
Dependent of symptom perception & symptom interpretation
Perception, interpretation & response
perception - do you notice it?
interpretation - what does it mean?
Response - how will you act upon it?
What is perception?
physical sensations are trivial:
- increase likelihood symptom perception
- painful/disruptive
- novel
- persistent
- pre-existing chronic disease
Attention –> symptom perception
differences in the attention given to internal and external states:
- increase symptom perception –> well-published illnes
- increased perception of symptoms –> Increased knowledge of symptoms (medical student’s disease)
- reduced symptom perception –> distractions
Emotion
= symptom perception
Personality traits
OCEAN:
Neuroticism/negative affectivity increases attention to somatic symptomatology
Symptom perception is affected by:
Gender - women more likely
Coping - repression = less likely
Social situations - context influences our motivations
Perception of vulnerability - stereotypes
Cognitions - expectations & self-fulfilling prophecies
Placebo & nocebo effects
favourable/unfavourable “treatment effects” that cannot be ascribed to mechanisms of treatment itself
–> expectations of a treatment:
Placebo = improvement
nocebo = worsening
Open vs hidden treatment (placebo)
open application (treatment) has the largest psychological effect on pain reduction
formation of expectations
= learning theories
- instructions
- conditioning
- observation
Verbal suggestion (analgesia=pijnstilling)
- can reduce pain in some people
- you will receive no treatment
! placebo analgesia can sometimes even match analgesia after active agent (echte pijnstilling)
! by nocebo information: reversal of topical analgesia possible
Placebo: conditioning
placebo more effective when first active treatment (conditioning = longterm, automatic & implicit)
Pain: placebo analgesia / nocebo hyperalgesia (meer pijn)
size of effect depends on:
- clinical or mechanism trial
- effects induced/learned
- type of pain: acute, experimental & procedural pain vs. chronic
Cobi verbal suggestion + conditioning = most effective
Informing about side effects can cause them
Breast cancer patients: more cognitive problems after information about these side effects
reinterpreting side effects
“symptoms indicate the treatment is working”